Comparative genomic analysis reveals metabolic flexibility of Woesearchaeota.
Nat Commun
; 12(1): 5281, 2021 09 06.
Article
in En
| MEDLINE
| ID: mdl-34489402
ABSTRACT
The archaeal phylum Woesearchaeota, within the DPANN superphylum, includes phylogenetically diverse microorganisms that inhabit various environments. Their biology is poorly understood due to the lack of cultured isolates. Here, we analyze datasets of Woesearchaeota 16S rRNA gene sequences and metagenome-assembled genomes to infer global distribution patterns, ecological preferences and metabolic capabilities. Phylogenomic analyses indicate that the phylum can be classified into ten subgroups, termed A-J. While a symbiotic lifestyle is predicted for most, some members of subgroup J might be host-independent. The genomes of several Woesearchaeota, including subgroup J, encode putative [FeFe] hydrogenases (known to be important for fermentation in other organisms), suggesting that these archaea might be anaerobic fermentative heterotrophs.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
RNA, Ribosomal, 16S
/
Archaea
/
Archaeal Proteins
/
RNA, Archaeal
/
Genome, Archaeal
/
Hydrogenase
Language:
En
Journal:
Nat Commun
Journal subject:
BIOLOGIA
/
CIENCIA
Year:
2021
Document type:
Article
Affiliation country:
China