Cas12a target search and cleavage on force-stretched DNA.

Losito, Marialucrezia; Smith, Quentin M; Newton, Matthew D; Cuomo, Maria Emanuela; Rueda, David S

Losito, Marialucrezia; Smith, Quentin M; Newton, Matthew D; Cuomo, Maria Emanuela; Rueda, David S.

Affiliation

Losito M; Department of Infectious Disease, Section of Virology, Faculty of Medicine, Imperial College London, London W12 0NN, UK. david.rueda@imperial.ac.uk.
Smith QM; Single Molecule Imaging Group, MRC London Institute of Medical Sciences, London W12 0NN, UK.
Newton MD; Discovery Sciences, AstraZeneca, Cambridge CB4 0WG, UK.
Cuomo ME; Department of Infectious Disease, Section of Virology, Faculty of Medicine, Imperial College London, London W12 0NN, UK. david.rueda@imperial.ac.uk.
Rueda DS; Single Molecule Imaging Group, MRC London Institute of Medical Sciences, London W12 0NN, UK.

Phys Chem Chem Phys ; 23(47): 26640-26644, 2021 Dec 08.

Article in En | MEDLINE | ID: mdl-34494640

Subject(s)

Bacterial Proteins/chemistry; CRISPR-Associated Proteins/chemistry; DNA/chemistry; Endodeoxyribonucleases/chemistry; CRISPR-Cas Systems; Models, Molecular; Optical Tweezers

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Proteins / DNA / Endodeoxyribonucleases / CRISPR-Associated Proteins Language: En Journal: Phys Chem Chem Phys Journal subject: BIOFISICA / QUIMICA Year: 2021 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

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