Time-resolved in vivo ubiquitinome profiling by DIA-MS reveals USP7 targets on a proteome-wide scale.

Steger, Martin; Demichev, Vadim; Backman, Mattias; Ohmayer, Uli; Ihmor, Phillip; Müller, Stefan; Ralser, Markus; Daub, Henrik

Steger, Martin; Demichev, Vadim; Backman, Mattias; Ohmayer, Uli; Ihmor, Phillip; Müller, Stefan; Ralser, Markus; Daub, Henrik.

Affiliation

Steger M; Evotec München GmbH, Am Klopferspitz 19a, Martinsried, Germany. martin.steger@evotec.com.
Demichev V; Charité - Universitätsmedizin Berlin, Department of Biochemistry, Berlin, Germany.
Backman M; The Francis Crick Institute, Molecular Biology of Metabolism Laboratory, London, UK.
Ohmayer U; The University of Cambridge, Department of Biochemistry and Cambridge Centre for Proteomics, Cambridge, UK.
Ihmor P; Evotec München GmbH, Am Klopferspitz 19a, Martinsried, Germany.
Müller S; Evotec München GmbH, Am Klopferspitz 19a, Martinsried, Germany.
Ralser M; Evotec München GmbH, Am Klopferspitz 19a, Martinsried, Germany.
Daub H; Evotec München GmbH, Am Klopferspitz 19a, Martinsried, Germany.

Nat Commun ; 12(1): 5399, 2021 09 13.

Article in En | MEDLINE | ID: mdl-34518535

Subject(s)

Neural Networks, Computer; Proteome/metabolism; Proteomics/methods; Tandem Mass Spectrometry/methods; Ubiquitin-Specific Peptidase 7/metabolism; Ubiquitination; Cell Line, Tumor; HCT116 Cells; Humans; Jurkat Cells; Signal Transduction; Substrate Specificity; Time Factors; Ubiquitin/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neural Networks, Computer / Proteome / Proteomics / Tandem Mass Spectrometry / Ubiquitination / Ubiquitin-Specific Peptidase 7 Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: Germany Country of publication: United kingdom

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