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NRXN1α+/- is associated with increased excitability in ASD iPSC-derived neurons.
Avazzadeh, Sahar; Quinlan, Leo R; Reilly, Jamie; McDonagh, Katya; Jalali, Amirhossein; Wang, Yanqin; McInerney, Veronica; Krawczyk, Janusz; Ding, Yicheng; Fitzgerald, Jacqueline; O'Sullivan, Matthew; Forman, Eva B; Lynch, Sally A; Ennis, Sean; Feerick, Niamh; Reilly, Richard; Li, Weidong; Shen, Xu; Yang, Guangming; Lu, Yin; Peeters, Hilde; Dockery, Peter; O'Brien, Timothy; Shen, Sanbing; Gallagher, Louise.
Affiliation
  • Avazzadeh S; School of Medicine, Regenerative Medicine Institute, Biomedical Science Building BMS-1021, National University of Ireland Galway, Dangan, Ireland.
  • Quinlan LR; Physiology and Cellular Physiology Research Laboratory, School of Medicine, CÚRAM SFI Centre for Research in Medical Devices, National University of Ireland (NUI), Galway, Ireland.
  • Reilly J; School of Medicine, Regenerative Medicine Institute, Biomedical Science Building BMS-1021, National University of Ireland Galway, Dangan, Ireland.
  • McDonagh K; School of Medicine, Regenerative Medicine Institute, Biomedical Science Building BMS-1021, National University of Ireland Galway, Dangan, Ireland.
  • Jalali A; School of Mathematical Sciences, University College Cork, Cork, Ireland.
  • Wang Y; School of Medicine, Regenerative Medicine Institute, Biomedical Science Building BMS-1021, National University of Ireland Galway, Dangan, Ireland.
  • McInerney V; Department of Physiology, College of Life Science, Hebei Normal University, Shijiazhuang, China.
  • Krawczyk J; HRB Clinical Research Facility, National University of Ireland (NUI), Galway, Ireland.
  • Ding Y; Department of Haematology, Galway University Hospital, Galway, Ireland.
  • Fitzgerald J; School of Medicine, Regenerative Medicine Institute, Biomedical Science Building BMS-1021, National University of Ireland Galway, Dangan, Ireland.
  • O'Sullivan M; Trinity Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland.
  • Forman EB; Trinity Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland.
  • Lynch SA; Children's University Hospital, Temple Street, Dublin, Ireland.
  • Ennis S; Children's University Hospital, Temple Street, Dublin, Ireland.
  • Feerick N; Department of Clinical Genetics, OLCHC, Dublin 12, Ireland.
  • Reilly R; School of Medicine and Medical Science, UCD Academic Centre On Rare Diseases, University College Dublin, Dublin, Ireland.
  • Li W; Centre for Bioengineering, Trinity College Institute of Neuroscience, School of Medicine, School of Engineering, Trinity College Dublin, Dublin, Ireland.
  • Shen X; Centre for Bioengineering, Trinity College Institute of Neuroscience, School of Medicine, School of Engineering, Trinity College Dublin, Dublin, Ireland.
  • Yang G; Bio-X Institutes, Key Laboratory for the Genetics of Development and Neuropsychiatric Disorders (Ministry of Education), Shanghai Key Laboratory of Psychotic Disorders, and Brain Science and Technology Research Center, Shanghai Jiao Tong University, Shanghai, China.
  • Lu Y; School of Medicine and Life Sciences, Nanjing University of Chinese Medicine, 138 Xianlin Road, Nanjing, 210023, China.
  • Peeters H; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
  • Dockery P; College of Pharmacy, Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Jiangsu Collaborative Innovation Center of Traditional Chinese Medicine (TCM) Prevention and Treatment of Tumor, Nanjing University of Chinese Medicine, Nanjing, 210023, Jiangsu, China.
  • O'Brien T; Centre for Human Genetics, University Hospital Leuven, KU Leuven, 3000, Leuven, Belgium.
  • Shen S; Centre for Microscopy and Imaging, Anatomy, School of Medicine, National University of Ireland (NUI), Galway, Ireland.
  • Gallagher L; School of Medicine, Regenerative Medicine Institute, Biomedical Science Building BMS-1021, National University of Ireland Galway, Dangan, Ireland.
BMC Neurosci ; 22(1): 56, 2021 09 15.
Article in En | MEDLINE | ID: mdl-34525970
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Calcium-Binding Proteins / Neural Cell Adhesion Molecules / Gene Regulatory Networks / Induced Pluripotent Stem Cells / Autism Spectrum Disorder / Neurons Type of study: Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Child / Child, preschool / Female / Humans / Male Language: En Journal: BMC Neurosci Journal subject: NEUROLOGIA Year: 2021 Document type: Article Affiliation country: Ireland Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Calcium-Binding Proteins / Neural Cell Adhesion Molecules / Gene Regulatory Networks / Induced Pluripotent Stem Cells / Autism Spectrum Disorder / Neurons Type of study: Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Child / Child, preschool / Female / Humans / Male Language: En Journal: BMC Neurosci Journal subject: NEUROLOGIA Year: 2021 Document type: Article Affiliation country: Ireland Country of publication: United kingdom