Giant cell tumour of bone around the knee: a systematic review of the functional and oncological outcomes.
EFORT Open Rev
; 6(8): 641-650, 2021 Aug.
Article
in En
| MEDLINE
| ID: mdl-34532071
ABSTRACT
Giant cell tumour of bone (GCT) is a relatively rare, locally aggressive benign neoplasm observed in the long bone epiphyseal-metaphyseal regions of young adults.The optimal treatment strategy for these tumours remains controversial, and a huge amount of contradictory data regarding the functional and oncological outcomes can be found. Therefore, we performed a systematic review intended to investigate the functional and oncological outcomes after surgical treatment of GCTs arising around the knee, namely in the distal femur and proximal tibia.A trend towards better oncological control was found using wide resections, nonetheless, curettage-based techniques achieve a highly acceptable recurrence rate with overall better knee function. A slight advantage favouring proximal tibia GCTs regarding the Musculoskeletal Tumor Society (MSTS) score was also observed.Prospective studies comparing groups of more homogeneous patients, tumours, and treatment options should be developed to obtain more conclusive and definitive results regarding the optimal strategy for treating GCTs. Cite this article EFORT Open Rev 2021;6641-650. DOI 10.1302/2058-5241.6.200154.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Type of study:
Observational_studies
/
Systematic_reviews
Language:
En
Journal:
EFORT Open Rev
Year:
2021
Document type:
Article
Affiliation country:
Portugal