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Management of breast cancer patients with BRCA gene mutations in Lebanon of the Middle East: perspectives and challenges.
El Saghir, Nagi S; Ghanem, Hady; El Karak, Fadi; Farhat, Fadi; Ghosn, Marwan; Makdessi, Joseph; Chouaib, Khouloud; Debs, Jamil; Tabchy, Adel B.
Affiliation
  • El Saghir NS; Division of Hematology Oncology, American University of Beirut Medical Center, Beirut, Lebanon.
  • Ghanem H; Division of Hematology Oncology, Lebanese American University Medical Center - Rizk Hospital, Beirut, Lebanon.
  • El Karak F; Department of Oncology-Hematology, School of Medicine, Saint Joseph University, Beirut, Lebanon.
  • Farhat F; Division of Hematology Oncology, Hammoud Hospital University Medical Center, Saida, Lebanon.
  • Ghosn M; Hematology Oncology Department, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.
  • Makdessi J; Hematology and Oncology Department, Saint George Hospital University Medical Center, Beirut, Lebanon.
  • Chouaib K; Oncology Department, Medical Affairs, Pfizer Africa - Middle East Region, Lebanon.
  • Debs J; Oncology Department, Medical Affairs, Pfizer Africa - Middle East Region, Lebanon.
  • Tabchy AB; Department of Hematology/Oncology, Saint-Joseph University - School of Medicine, Beirut, Lebanon.
Hosp Pract (1995) ; 49(5): 325-329, 2021 Dec.
Article in En | MEDLINE | ID: mdl-34547975
ABSTRACT

BACKGROUND:

This commentary explores and discusses the challenges oncologists face in diagnosing and managing breast cancer patients with BRCA gene mutations in Lebanon and the Middle East.

METHODS:

Key opinion leaders shared their recommendations to achieve better patient outcomes and satisfaction based on evidence-based medicine and their clinical experience in BRCA management.

RESULTS:

Challenges associated with BRCA management can be divided into four main levels physicians, patients, test, and treatment factors. More genetic counselors are to be identified given their important role in the management of individuals with BRCA gene mutations.

CONCLUSION:

Genetic counseling, continuing education, infrastructure, testing, expertise, and financial support are needed to fulfill the unmet needs in the management of BRCA mutation carriers.
Subject(s)
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Genes, BRCA1 / Genes, BRCA2 Type of study: Guideline / Prognostic_studies Limits: Female / Humans Country/Region as subject: Asia Language: En Journal: Hosp Pract (1995) Journal subject: HOSPITAIS Year: 2021 Document type: Article Affiliation country: Lebanon

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Genes, BRCA1 / Genes, BRCA2 Type of study: Guideline / Prognostic_studies Limits: Female / Humans Country/Region as subject: Asia Language: En Journal: Hosp Pract (1995) Journal subject: HOSPITAIS Year: 2021 Document type: Article Affiliation country: Lebanon