Bile reflux and hypopharyngeal cancer (Review).

Vageli, Dimitra P; Doukas, Sotirios G; Doukas, Panagiotis G; Judson, Benjamin L

Vageli, Dimitra P; Doukas, Sotirios G; Doukas, Panagiotis G; Judson, Benjamin L.

Affiliation

Vageli DP; The Yale Larynx Laboratory, Department of Surgery, Yale School of Medicine, New Haven, CT 06510, USA.
Doukas SG; The Yale Larynx Laboratory, Department of Surgery, Yale School of Medicine, New Haven, CT 06510, USA.
Doukas PG; The Yale Larynx Laboratory, Department of Surgery, Yale School of Medicine, New Haven, CT 06510, USA.
Judson BL; The Yale Larynx Laboratory, Department of Surgery, Yale School of Medicine, New Haven, CT 06510, USA.

Oncol Rep ; 46(5)2021 Nov.

Article in En | MEDLINE | ID: mdl-34558652

Subject(s)

Bile Reflux/complications; Bile Reflux/pathology; Hypopharyngeal Neoplasms/etiology; Hypopharyngeal Neoplasms/pathology; Bile Acids and Salts/metabolism; Carcinoma, Squamous Cell/etiology; Carcinoma, Squamous Cell/pathology; DNA Damage; Humans; NF-kappa B/metabolism; RNA, Messenger/metabolism; Risk Factors; STAT3 Transcription Factor/metabolism; Signal Transduction; Tumor Suppressor Protein p53/metabolism

Key words

DNA damage; NFκB; bile reflux; conjugated bile acids; deoxycholic acid; head and neck cancer; hypopharyngeal cancer; hypopharyngeal squamous cell carcinoma; in vivo; laryngopharyngeal reflux

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hypopharyngeal Neoplasms / Bile Reflux Type of study: Etiology_studies / Risk_factors_studies Limits: Humans Language: En Journal: Oncol Rep Journal subject: NEOPLASIAS Year: 2021 Document type: Article Affiliation country: United States Country of publication: Greece

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