Metformin Ameliorates Neuronal Necroptosis after Intracerebral Hemorrhage by Activating AMPK.

Lin, Chenhan; Yang, Kaichuang; Zhang, Guoqiang; Yu, Jun

Lin, Chenhan; Yang, Kaichuang; Zhang, Guoqiang; Yu, Jun.

Affiliation

Lin C; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Yang K; Department of Neurosurgery, Zhejiang Provincial People\'s Hospital, Hangzhou, Zhejiang, China.
Zhang G; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Yu J; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.

Curr Neurovasc Res ; 18(3): 351-359, 2021.

Article in En | MEDLINE | ID: mdl-34561980

Subject(s)

Diabetes Mellitus, Type 2; Metformin; AMP-Activated Protein Kinases; Cerebral Hemorrhage/complications; Diabetes Mellitus, Type 2/complications; Humans; Metformin/pharmacology; Metformin/therapeutic use; Necroptosis

Key words

AMPK; ICH; metformin; necroptosis; rotarod test; western blot analysis.

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diabetes Mellitus, Type 2 / Metformin Limits: Humans Language: En Journal: Curr Neurovasc Res Journal subject: ANGIOLOGIA / NEUROLOGIA Year: 2021 Document type: Article Affiliation country: China Country of publication: United Arab Emirates

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