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Circulating extracellular vesicles of patients with steroid-sensitive nephrotic syndrome have higher RAC1 and induce recapitulation of nephrotic syndrome phenotype in podocytes.
Eroglu, Fehime K; Yazar, Volkan; Guler, Ulku; Yildirim, Muzaffer; Yildirim, Tugce; Gungor, Tulin; Celikkaya, Evra; Karakaya, Deniz; Turay, Nilsu; Ciftci Dede, Eda; Korkusuz, Petek; Salih, Bekir; Bulbul, Mehmet; Gursel, Ihsan.
Affiliation
  • Eroglu FK; Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey.
  • Yazar V; SBU Dr Sami Ulus Maternity Child Health and Diseases Training and Research Hospital, Ankara, Turkey.
  • Guler U; Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey.
  • Yildirim M; Department of Chemistry, Hacettepe University, Ankara, Turkey.
  • Yildirim T; Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey.
  • Gungor T; Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey.
  • Celikkaya E; SBU Dr Sami Ulus Maternity Child Health and Diseases Training and Research Hospital, Ankara, Turkey.
  • Karakaya D; SBU Dr Sami Ulus Maternity Child Health and Diseases Training and Research Hospital, Ankara, Turkey.
  • Turay N; SBU Dr Sami Ulus Maternity Child Health and Diseases Training and Research Hospital, Ankara, Turkey.
  • Ciftci Dede E; Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey.
  • Korkusuz P; Department of Histology and Embryology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
  • Salih B; Department of Histology and Embryology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
  • Bulbul M; Department of Chemistry, Hacettepe University, Ankara, Turkey.
  • Gursel I; SBU Dr Sami Ulus Maternity Child Health and Diseases Training and Research Hospital, Ankara, Turkey.
Am J Physiol Renal Physiol ; 321(5): F659-F673, 2021 11 01.
Article in En | MEDLINE | ID: mdl-34569252

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rac1 GTP-Binding Protein / Podocytes / Extracellular Vesicles / Nephrotic Syndrome Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies Limits: Adolescent / Child / Child, preschool / Female / Humans / Male Language: En Journal: Am J Physiol Renal Physiol Journal subject: FISIOLOGIA / NEFROLOGIA Year: 2021 Document type: Article Affiliation country: Turkey

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rac1 GTP-Binding Protein / Podocytes / Extracellular Vesicles / Nephrotic Syndrome Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies Limits: Adolescent / Child / Child, preschool / Female / Humans / Male Language: En Journal: Am J Physiol Renal Physiol Journal subject: FISIOLOGIA / NEFROLOGIA Year: 2021 Document type: Article Affiliation country: Turkey