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LEFTY-PITX2 signaling pathway is critical for generation of mature and ventricular cardiac organoids in human pluripotent stem cell-derived cardiac mesoderm cells.
Song, Myeong-Hwa; Choi, Seung-Cheol; Noh, Ji-Min; Joo, Hyung Joon; Park, Chi-Yeon; Cha, Jung-Joon; Ahn, Tae Hoon; Ko, Tae Hee; Choi, Jong-Il; Na, Ji Eun; Rhyu, Im Joo; Jang, Yongjun; Park, Yongdoo; Gim, Jeong-An; Kim, Jong-Hoon; Lim, Do-Sun.
Affiliation
  • Song MH; Department of Cardiology, Cardiovascular Center, College of Medicine, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, South Korea.
  • Choi SC; Department of Cardiology, Cardiovascular Center, College of Medicine, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, South Korea; R&D Center for Companion Diagnostic, SOL Bio Corporation, Suite 510, 27, Seongsui-ro7-gil, Seongdong-gu, Seoul, 04780, South Korea.
  • Noh JM; Department of Cardiology, Cardiovascular Center, College of Medicine, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, South Korea.
  • Joo HJ; Department of Cardiology, Cardiovascular Center, College of Medicine, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, South Korea.
  • Park CY; Department of Cardiology, Cardiovascular Center, College of Medicine, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, South Korea.
  • Cha JJ; Department of Cardiology, Cardiovascular Center, College of Medicine, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, South Korea.
  • Ahn TH; Department of Cardiology, Cardiovascular Center, College of Medicine, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, South Korea.
  • Ko TH; Division of Cardiology, Department of Internal Medicine, Korea University College of Medicine and Korea University Anam Hospital, Seoul, 02841, South Korea.
  • Choi JI; Division of Cardiology, Department of Internal Medicine, Korea University College of Medicine and Korea University Anam Hospital, Seoul, 02841, South Korea.
  • Na JE; Department of Anatomy, College of Medicine, Korea University, Seoul, 02841, South Korea.
  • Rhyu IJ; Department of Anatomy, College of Medicine, Korea University, Seoul, 02841, South Korea.
  • Jang Y; Department of Biomedical Sciences, College of Medicine, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, South Korea.
  • Park Y; Department of Biomedical Sciences, College of Medicine, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, South Korea.
  • Gim JA; Medical Science Research Center, College of Medicine, Korea University Guro Hospital, Seoul,08308, South Korea.
  • Kim JH; Laboratory of Stem Cells and Tissue Regeneration, Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, 02841, South Korea.
  • Lim DS; Department of Cardiology, Cardiovascular Center, College of Medicine, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, South Korea. Electronic address: dslmd@kumc.or.kr.
Biomaterials ; 278: 121133, 2021 11.
Article in En | MEDLINE | ID: mdl-34571434
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Homeodomain Proteins / Myocytes, Cardiac / Pluripotent Stem Cells / Left-Right Determination Factors / Induced Pluripotent Stem Cells Type of study: Prognostic_studies Limits: Humans Language: En Journal: Biomaterials Year: 2021 Document type: Article Affiliation country: South Korea Country of publication: Netherlands
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Homeodomain Proteins / Myocytes, Cardiac / Pluripotent Stem Cells / Left-Right Determination Factors / Induced Pluripotent Stem Cells Type of study: Prognostic_studies Limits: Humans Language: En Journal: Biomaterials Year: 2021 Document type: Article Affiliation country: South Korea Country of publication: Netherlands