The Role of Intracellular Trafficking of Notch Receptors in Ligand-Independent Notch Activation.

Hounjet, Judith; Vooijs, Marc

Hounjet, Judith; Vooijs, Marc.

Affiliation

Hounjet J; Department of Radiation Oncology (MAASTRO), GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, P.O. 616, 6200 MD Maastricht, The Netherlands.
Vooijs M; Department of Radiation Oncology (MAASTRO), GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, P.O. 616, 6200 MD Maastricht, The Netherlands.

Biomolecules ; 11(9)2021 09 16.

Article in En | MEDLINE | ID: mdl-34572582

Subject(s)

Receptors, Notch/metabolism; Animals; Endosomes/metabolism; Humans; Ligands; Molecular Targeted Therapy; Protein Transport; Signal Transduction

Key words

Drosophila; Notch signaling; intracellular trafficking; ligand-independent; mammals; therapeutic targeting

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Notch Limits: Animals / Humans Language: En Journal: Biomolecules Year: 2021 Document type: Article Affiliation country: Netherlands Country of publication: Switzerland

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