Cystine/Glutamate Antiporter in Schizophrenia: From Molecular Mechanism to Novel Biomarker and Treatment.

Hung, Chung-Chieh; Lin, Chieh-Hsin; Lane, Hsien-Yuan

Hung, Chung-Chieh; Lin, Chieh-Hsin; Lane, Hsien-Yuan.

Affiliation

Hung CC; Institute of Clinical Medical Science, China Medical University, Taichung 40402, Taiwan.
Lin CH; Department of Psychiatry, China Medical University Hospital, Taichung 40402, Taiwan.
Lane HY; Institute of Clinical Medical Science, China Medical University, Taichung 40402, Taiwan.

Int J Mol Sci ; 22(18)2021 Sep 08.

Article in En | MEDLINE | ID: mdl-34575878

Subject(s)

Antiporters/genetics; Antiporters/metabolism; Cystine/metabolism; Disease Susceptibility; Glutamic Acid/metabolism; Schizophrenia/etiology; Schizophrenia/metabolism; Animals; Biological Transport; Biomarkers; Disease Management; Humans; Neurons/metabolism; Neurotransmitter Agents/metabolism; Oxidative Stress/drug effects; Precision Medicine/methods; Schizophrenia/diagnosis; Schizophrenia/therapy; Synaptic Transmission

Key words

biomarker; cystine/glutamate antiporter; schizophrenia; system xc−

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Schizophrenia / Antiporters / Glutamic Acid / Cystine / Disease Susceptibility Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Int J Mol Sci Year: 2021 Document type: Article Affiliation country: Taiwan Country of publication: Switzerland

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