In Vivo Expansion of Antigen-Specific Regulatory T Cells through Staggered Fc.IL-2 Mutein Dosing and Antigen-Specific Immunotherapy.

Pham, Minh N; Khoryati, Liliane; Jamison, Braxton L; Hayes, Erika; Sullivan, Jenna M; Campbell, Daniel J; Gavin, Marc A

Pham, Minh N; Khoryati, Liliane; Jamison, Braxton L; Hayes, Erika; Sullivan, Jenna M; Campbell, Daniel J; Gavin, Marc A.

Affiliation

Pham MN; Benaroya Research Institute, Seattle, WA; and.
Khoryati L; Benaroya Research Institute, Seattle, WA; and.
Jamison BL; Benaroya Research Institute, Seattle, WA; and.
Hayes E; Benaroya Research Institute, Seattle, WA; and.
Sullivan JM; Benaroya Research Institute, Seattle, WA; and.
Campbell DJ; Benaroya Research Institute, Seattle, WA; and mgavin@omeros.com dcampbell@benaroyaresearch.org.
Gavin MA; Benaroya Research Institute, Seattle, WA; and mgavin@omeros.com dcampbell@benaroyaresearch.org.

Immunohorizons ; 5(9): 782-791, 2021 09 28.

Article in En | MEDLINE | ID: mdl-34583939

Subject(s)

Antigens/immunology; Interleukin-2/immunology; Recombinant Fusion Proteins/immunology; T-Lymphocytes, Regulatory/immunology; Animals; Autoimmune Diseases/immunology; Autoimmune Diseases/therapy; Cells, Cultured; Female; Humans; Hypersensitivity/immunology; Hypersensitivity/therapy; Immune Tolerance; Immunotherapy, Adoptive/methods; Interleukin-2/genetics; Mice; Models, Animal; Mutation; Primary Cell Culture/methods; Recombinant Fusion Proteins/genetics; T-Lymphocytes, Regulatory/transplantation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Recombinant Fusion Proteins / Interleukin-2 / T-Lymphocytes, Regulatory / Antigens Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Immunohorizons Year: 2021 Document type: Article Country of publication: United States

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