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Targeting INMT and interrupting its methylation pathway for the treatment of castration resistant prostate cancer.
Zhong, Shangwei; Jeong, Ji-Hak; Huang, Changhao; Chen, Xueyan; Dickinson, Shohreh Iravani; Dhillon, Jasreman; Yang, Li; Luo, Jun-Li.
Affiliation
  • Zhong S; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA.
  • Jeong JH; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA.
  • Huang C; College of Pharmacy, Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, 41566, Republic of Korea.
  • Chen X; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA.
  • Dickinson SI; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA.
  • Dhillon J; Department of Pathology, Moffitt Cancer Center, 2902 Magnolia Drive, Tampa, FL, 33612, USA.
  • Yang L; Department of Pathology, Moffitt Cancer Center, 2902 Magnolia Drive, Tampa, FL, 33612, USA.
  • Luo JL; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA. yangli0727@zzu.edu.cn.
J Exp Clin Cancer Res ; 40(1): 307, 2021 Sep 29.
Article in En | MEDLINE | ID: mdl-34587977
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation, Enzymologic / Gene Expression Regulation, Neoplastic / Histone-Lysine N-Methyltransferase / DNA Methylation / Enzyme Inhibitors / Prostatic Neoplasms, Castration-Resistant / Methyltransferases Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: J Exp Clin Cancer Res Year: 2021 Document type: Article Affiliation country: United States Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation, Enzymologic / Gene Expression Regulation, Neoplastic / Histone-Lysine N-Methyltransferase / DNA Methylation / Enzyme Inhibitors / Prostatic Neoplasms, Castration-Resistant / Methyltransferases Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: J Exp Clin Cancer Res Year: 2021 Document type: Article Affiliation country: United States Country of publication: United kingdom