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Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality.
Nakanishi, Tomoko; Pigazzini, Sara; Degenhardt, Frauke; Cordioli, Mattia; Butler-Laporte, Guillaume; Maya-Miles, Douglas; Bujanda, Luis; Bouysran, Youssef; Niemi, Mari Ek; Palom, Adriana; Ellinghaus, David; Khan, Atlas; Martínez-Bueno, Manuel; Rolker, Selina; Amitrano, Sara; Roade Tato, Luisa; Fava, Francesca; Spinner, Christoph D; Prati, Daniele; Bernardo, David; Garcia, Federico; Darcis, Gilles; Fernández-Cadenas, Israel; Holter, Jan Cato; Banales, Jesus M; Frithiof, Robert; Kiryluk, Krzysztof; Duga, Stefano; Asselta, Rosanna; Pereira, Alexandre C; Romero-Gómez, Manuel; Nafría-Jiménez, Beatriz; Hov, Johannes R; Migeotte, Isabelle; Renieri, Alessandra; Planas, Anna M; Ludwig, Kerstin U; Buti, Maria; Rahmouni, Souad; Alarcón-Riquelme, Marta E; Schulte, Eva C; Franke, Andre; Karlsen, Tom H; Valenti, Luca; Zeberg, Hugo; Richards, J Brent; Ganna, Andrea.
Affiliation
  • Nakanishi T; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.
  • Pigazzini S; Department of Human Genetics and.
  • Degenhardt F; Centre for Clinical Epidemiology, Department of Medicine, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec, Canada.
  • Cordioli M; Kyoto-McGill International Collaborative School in Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Butler-Laporte G; Japan Society for the Promotion of Science, Tokyo, Japan.
  • Maya-Miles D; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.
  • Bujanda L; University of Milano-Bicocca, Milano, Italy.
  • Bouysran Y; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany.
  • Niemi ME; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.
  • Palom A; Centre for Clinical Epidemiology, Department of Medicine, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec, Canada.
  • Ellinghaus D; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Quebec, Canada.
  • Khan A; Digestive Diseases Unit, Virgen del Rocio University Hospital, Institute of Biomedicine of Seville, University of Seville, Seville, Spain.
  • Martínez-Bueno M; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.
  • Rolker S; Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute, Donostia University Hospital, University of the Basque Country (UPV/EHU), CIBERehd, Ikerbasque, San Sebastian, Spain.
  • Amitrano S; Centre de Génétique Humaine, Hôpital Erasme, Université Libre de Bruxelles (ULB), Brussels, Belgium.
  • Roade Tato L; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.
  • Fava F; Liver Unit, Department of Internal Medicine, Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
  • Spinner CD; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany.
  • Prati D; Novo Nordisk Foundation Center for Protein Research, Disease Systems Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Bernardo D; Division of Nephrology, Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
  • Garcia F; GENYO, Centre for Genomics and Oncological Research: Pfizer/University of Granada/Andalusian Regional Government, Granada, Spain.
  • Darcis G; nstitute of Human Genetics, University Hospital Bonn, Medical Faculty University of Bonn, Bonn, Germany.
  • Fernández-Cadenas I; Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Siena, Italy.
  • Holter JC; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.
  • Banales JM; Liver Unit, Department of Internal Medicine, Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
  • Frithiof R; Departament de Medicina: Bellaterra, Universitat Autònoma de Barcelona, Barcelona, Spain.
  • Kiryluk K; Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Siena, Italy.
  • Duga S; Medical Genetics and.
  • Asselta R; Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Italy.
  • Nafría-Jiménez B; Technical University of Munich, School of Medicine, University Hospital Rechts der Isar, Department of Internal Medicine II, Munich, Germany.
  • Hov JR; Department of Transfusion Medicine and Hematology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano, Milano, Italy.
  • Migeotte I; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.
  • Renieri A; Mucosal Immunology Lab, Unit of Excellence Institute of Biomedicine and Molecular Genetics (IBGM), University of Valladolid-CSIC, Valladolid, Spain.
  • Planas AM; Hospital Universitario Clinico San Cecilio, Granada, Spain.
  • Ludwig KU; Instituto de Investigación Ibs.Granada, Granada, Spain.
  • Buti M; University of Liege, GIGA-Insitute, Liege, Belgium.
  • Rahmouni S; Liege University Hospital (CHU of Liege), Liege, Belgium.
  • Alarcón-Riquelme ME; Stroke Pharmacogenomics and Genetics Group, Biomedical Research Institute Sant Pau (IIB Sant Pau), Barcelona, Spain.
  • Schulte EC; Department of Microbiology, Oslo University Hospital, Oslo, Norway.
  • Franke A; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Karlsen TH; Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute, Donostia University Hospital, University of the Basque Country (UPV/EHU), CIBERehd, Ikerbasque, San Sebastian, Spain.
  • Valenti L; Department of Biochemistry and Genetics, School of Sciences, University of Navarra, Pamplona, Spain.
  • Zeberg H; Department of Surgical Sciences, Anaesthesiology and Intensive Care Medicine, Uppsala University, Uppsala, Sweden.
  • Richards JB; Division of Nephrology, Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
  • Ganna A; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.
J Clin Invest ; 131(23)2021 12 01.
Article in En | MEDLINE | ID: mdl-34597274
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymorphism, Genetic / Chromosomes, Human, Pair 3 / Alleles / Genetic Loci / Gene Frequency / SARS-CoV-2 / COVID-19 Type of study: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Aspects: Patient_preference Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: J Clin Invest Year: 2021 Document type: Article Affiliation country: Finland Country of publication: United States
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymorphism, Genetic / Chromosomes, Human, Pair 3 / Alleles / Genetic Loci / Gene Frequency / SARS-CoV-2 / COVID-19 Type of study: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Aspects: Patient_preference Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: J Clin Invest Year: 2021 Document type: Article Affiliation country: Finland Country of publication: United States