MicroRNA-26a systemic administration attenuates tumor formation in hepatocellular carcinoma mouse model.

Badr, Abeer M; El-Ahwany, Eman; Goda, Lamiaa; Nagy, Faten; Helal, Noha; El Deeb, Somaya

Badr, Abeer M; El-Ahwany, Eman; Goda, Lamiaa; Nagy, Faten; Helal, Noha; El Deeb, Somaya.

Affiliation

Badr AM; Zoology Department, Faculty of Science, Cairo University, Giza, Egypt.
El-Ahwany E; Immunology Department, Theodor Bilharz Research Institute (TBRI), Giza, Egypt.
Goda L; Zoology Department, Faculty of Science, Cairo University, Giza, Egypt.
Nagy F; Immunology Department, Theodor Bilharz Research Institute (TBRI), Giza, Egypt.
Helal N; Pathology Department, Theodor Bilharz Research Institute (TBRI), Giza, Egypt.
El Deeb S; Zoology Department, Faculty of Science, Cairo University, Giza, Egypt.

Pak J Pharm Sci ; 34(3): 925-932, 2021 May.

Article in En | MEDLINE | ID: mdl-34602415

Subject(s)

Carcinoma, Hepatocellular/metabolism; Liver Neoplasms, Experimental/metabolism; Liver Neoplasms/metabolism; Liver/drug effects; MicroRNAs/pharmacology; Alkylating Agents/toxicity; Animals; Apoptosis/drug effects; Biomarkers/metabolism; Carcinoma, Hepatocellular/genetics; Carcinoma, Hepatocellular/pathology; Caspase 3/drug effects; Caspase 3/metabolism; Cytokines/drug effects; Cytokines/metabolism; Diethylnitrosamine/toxicity; Interleukin-10/metabolism; Interleukin-2/metabolism; Liver/metabolism; Liver/pathology; Liver Neoplasms/genetics; Liver Neoplasms/pathology; Liver Neoplasms, Experimental/genetics; Liver Neoplasms, Experimental/pathology; Mice; Protein Precursors/drug effects; Protein Precursors/metabolism; Prothrombin/drug effects; Prothrombin/metabolism; Reverse Transcriptase Polymerase Chain Reaction; Survivin/drug effects; Survivin/metabolism; T-Lymphocytes, Helper-Inducer/drug effects; T-Lymphocytes, Helper-Inducer/metabolism; Tumor Necrosis Factor-alpha/drug effects; Tumor Necrosis Factor-alpha/metabolism; Vascular Endothelial Growth Factor A/drug effects; Vascular Endothelial Growth Factor A/metabolism; alpha-Fetoproteins/drug effects; alpha-Fetoproteins/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Hepatocellular / MicroRNAs / Liver / Liver Neoplasms / Liver Neoplasms, Experimental Type of study: Prognostic_studies Language: En Journal: Pak J Pharm Sci Journal subject: FARMACIA / FARMACOLOGIA / QUIMICA Year: 2021 Document type: Article Affiliation country: Egypt Country of publication: Pakistan

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