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The protein tyrosine kinase inhibitor genistein suppresses hypoxia-induced atrial natriuretic peptide secretion mediated by the PI3K/Akt-HIF-1α pathway in isolated beating rat atria.
Zhang, Qiu-Li; Li, Ping; Hong, Lan; Li, Rui-Zhuang; Wang, Jia-Qi; Cui, Xun.
Affiliation
  • Zhang QL; Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
  • Li P; Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
  • Hong L; Department of Physiology, School of Medical Sciences, Yanbian University, Yanji, China.
  • Li RZ; Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
  • Wang JQ; Affiliated Hospital of Inner Mongolia University for the Nationalities, Tongliao, Neimenggu, China.
  • Cui X; Department of Physiology, School of Medical Sciences, Yanbian University, Yanji, China.
Can J Physiol Pharmacol ; 99(11): 1184-1190, 2021 Nov.
Article in En | MEDLINE | ID: mdl-34612711
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein-Tyrosine Kinases / Signal Transduction / Atrial Natriuretic Factor / Genistein / Phosphatidylinositol 3-Kinases / Protein Kinase Inhibitors / Proto-Oncogene Proteins c-akt / Hypoxia-Inducible Factor 1, alpha Subunit / Heart Atria / Hypoxia Type of study: Prognostic_studies Limits: Animals Language: En Journal: Can J Physiol Pharmacol Year: 2021 Document type: Article Affiliation country: China Country of publication: Canada
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein-Tyrosine Kinases / Signal Transduction / Atrial Natriuretic Factor / Genistein / Phosphatidylinositol 3-Kinases / Protein Kinase Inhibitors / Proto-Oncogene Proteins c-akt / Hypoxia-Inducible Factor 1, alpha Subunit / Heart Atria / Hypoxia Type of study: Prognostic_studies Limits: Animals Language: En Journal: Can J Physiol Pharmacol Year: 2021 Document type: Article Affiliation country: China Country of publication: Canada