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Probing the distinct chemosensitivity of Plasmodium vivax liver stage parasites and demonstration of 8-aminoquinoline radical cure activity in vitro.
Maher, Steven P; Vantaux, Amélie; Chaumeau, Victor; Chua, Adeline C Y; Cooper, Caitlin A; Andolina, Chiara; Péneau, Julie; Rouillier, Mélanie; Rizopoulos, Zaira; Phal, Sivchheng; Piv, Eakpor; Vong, Chantrea; Phen, Sreyvouch; Chhin, Chansophea; Tat, Baura; Ouk, Sivkeng; Doeurk, Bros; Kim, Saorin; Suriyakan, Sangrawee; Kittiphanakun, Praphan; Awuku, Nana Akua; Conway, Amy J; Jiang, Rays H Y; Russell, Bruce; Bifani, Pablo; Campo, Brice; Nosten, François; Witkowski, Benoît; Kyle, Dennis E.
Affiliation
  • Maher SP; Center for Tropical and Emerging Global Diseases, University of Georgia, 500 DW Brooks Dr. Suite 370, Athens, GA, 30602, USA. steven.maher@uga.edu.
  • Vantaux A; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 5 Boulevard Monivong, PO Box 983, Phnom Penh, 12201, Cambodia.
  • Chaumeau V; Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 68/30 Bantung Rd., Mae Sot, Tak, 63110, Thailand.
  • Chua ACY; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine Research Building, University of Oxford, Old Road Campus, Oxford, UK.
  • Cooper CA; Infectious Diseases Laboratories (ID Labs), Agency for Science, Technology and Research (A*STAR), Immunos, Biopolis, Singapore, 138648, Singapore.
  • Andolina C; Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.
  • Péneau J; Center for Tropical and Emerging Global Diseases, University of Georgia, 500 DW Brooks Dr. Suite 370, Athens, GA, 30602, USA.
  • Rouillier M; Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 68/30 Bantung Rd., Mae Sot, Tak, 63110, Thailand.
  • Rizopoulos Z; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine Research Building, University of Oxford, Old Road Campus, Oxford, UK.
  • Phal S; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 5 Boulevard Monivong, PO Box 983, Phnom Penh, 12201, Cambodia.
  • Piv E; Medicines for Malaria Venture (MMV), Route de Pré-Bois 20, 1215, Geneva, Switzerland.
  • Vong C; Medicines for Malaria Venture (MMV), Route de Pré-Bois 20, 1215, Geneva, Switzerland.
  • Phen S; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 5 Boulevard Monivong, PO Box 983, Phnom Penh, 12201, Cambodia.
  • Chhin C; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 5 Boulevard Monivong, PO Box 983, Phnom Penh, 12201, Cambodia.
  • Tat B; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 5 Boulevard Monivong, PO Box 983, Phnom Penh, 12201, Cambodia.
  • Ouk S; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 5 Boulevard Monivong, PO Box 983, Phnom Penh, 12201, Cambodia.
  • Doeurk B; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 5 Boulevard Monivong, PO Box 983, Phnom Penh, 12201, Cambodia.
  • Kim S; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 5 Boulevard Monivong, PO Box 983, Phnom Penh, 12201, Cambodia.
  • Suriyakan S; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 5 Boulevard Monivong, PO Box 983, Phnom Penh, 12201, Cambodia.
  • Kittiphanakun P; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 5 Boulevard Monivong, PO Box 983, Phnom Penh, 12201, Cambodia.
  • Awuku NA; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 5 Boulevard Monivong, PO Box 983, Phnom Penh, 12201, Cambodia.
  • Conway AJ; Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 68/30 Bantung Rd., Mae Sot, Tak, 63110, Thailand.
  • Jiang RHY; Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 68/30 Bantung Rd., Mae Sot, Tak, 63110, Thailand.
  • Russell B; Center for Tropical and Emerging Global Diseases, University of Georgia, 500 DW Brooks Dr. Suite 370, Athens, GA, 30602, USA.
  • Bifani P; Department of Global Health, College of Public Health, Center for Global Health and Infectious Disease Research, University of South Florida, 3720 Spectrum Blvd Suite 402, Tampa, FL, 33612, USA.
  • Campo B; Department of Global Health, College of Public Health, Center for Global Health and Infectious Disease Research, University of South Florida, 3720 Spectrum Blvd Suite 402, Tampa, FL, 33612, USA.
  • Nosten F; Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.
  • Witkowski B; Infectious Diseases Laboratories (ID Labs), Agency for Science, Technology and Research (A*STAR), Immunos, Biopolis, Singapore, 138648, Singapore.
  • Kyle DE; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117545, Singapore.
Sci Rep ; 11(1): 19905, 2021 10 07.
Article in En | MEDLINE | ID: mdl-34620901
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium vivax / Malaria, Vivax / Parasitic Sensitivity Tests / Aminoquinolines / Liver / Antimalarials Type of study: Prognostic_studies Limits: Humans Language: En Journal: Sci Rep Year: 2021 Document type: Article Affiliation country: United States Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium vivax / Malaria, Vivax / Parasitic Sensitivity Tests / Aminoquinolines / Liver / Antimalarials Type of study: Prognostic_studies Limits: Humans Language: En Journal: Sci Rep Year: 2021 Document type: Article Affiliation country: United States Country of publication: United kingdom