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Inherited human c-Rel deficiency disrupts myeloid and lymphoid immunity to multiple infectious agents.
Lévy, Romain; Langlais, David; Béziat, Vivien; Rapaport, Franck; Rao, Geetha; Lazarov, Tomi; Bourgey, Mathieu; Zhou, Yu J; Briand, Coralie; Moriya, Kunihiko; Ailal, Fatima; Avery, Danielle T; Markle, Janet; Lim, Ai Ing; Ogishi, Masato; Yang, Rui; Pelham, Simon; Emam, Mehdi; Migaud, Mélanie; Deswarte, Caroline; Habib, Tanwir; Saraiva, Luis R; Moussa, Eman A; Guennoun, Andrea; Boisson, Bertrand; Belkaya, Serkan; Martinez-Barricarte, Ruben; Rosain, Jérémie; Belkadi, Aziz; Breton, Sylvain; Payne, Kathryn; Benhsaien, Ibtihal; Plebani, Alessandro; Lougaris, Vassilios; Di Santo, James P; Neven, Bénédicte; Abel, Laurent; Ma, Cindy S; Bousfiha, Ahmed Aziz; Marr, Nico; Bustamante, Jacinta; Liu, Kang; Gros, Philippe; Geissmann, Frédéric; Tangye, Stuart G; Casanova, Jean-Laurent; Puel, Anne.
Affiliation
  • Lévy R; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
  • Langlais D; University of Paris, Imagine Institute, Paris, France.
  • Béziat V; Pediatric Immunology, Hematology and Rheumatology Unit, Necker Hospital for Sick Children, AP-HP, Paris, France.
  • Rapaport F; McGill University, Montreal, Quebec, Canada.
  • Rao G; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
  • Lazarov T; University of Paris, Imagine Institute, Paris, France.
  • Bourgey M; St. Giles Laboratory of Human Genetics of Infectious Diseases, The Rockefeller University, New York, New York, USA.
  • Zhou YJ; St. Giles Laboratory of Human Genetics of Infectious Diseases, The Rockefeller University, New York, New York, USA.
  • Briand C; Garvan Institute, Darlinghurst, New South Wales 2010, Australia.
  • Moriya K; Memorial Sloan Kettering Institute, New York, New York, USA.
  • Ailal F; McGill University, Montreal, Quebec, Canada.
  • Avery DT; Columbia University, New York, New York, USA.
  • Markle J; Pediatric Immunology, Hematology and Rheumatology Unit, Necker Hospital for Sick Children, AP-HP, Paris, France.
  • Lim AI; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
  • Ogishi M; University of Paris, Imagine Institute, Paris, France.
  • Yang R; King Hassan II University, Casablanca, Morocco.
  • Pelham S; Garvan Institute, Darlinghurst, New South Wales 2010, Australia.
  • Emam M; St. Giles Laboratory of Human Genetics of Infectious Diseases, The Rockefeller University, New York, New York, USA.
  • Migaud M; Pasteur Institute, Paris, France.
  • Deswarte C; St. Giles Laboratory of Human Genetics of Infectious Diseases, The Rockefeller University, New York, New York, USA.
  • Habib T; St. Giles Laboratory of Human Genetics of Infectious Diseases, The Rockefeller University, New York, New York, USA.
  • Saraiva LR; St. Giles Laboratory of Human Genetics of Infectious Diseases, The Rockefeller University, New York, New York, USA.
  • Moussa EA; McGill University, Montreal, Quebec, Canada.
  • Guennoun A; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
  • Boisson B; University of Paris, Imagine Institute, Paris, France.
  • Belkaya S; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
  • Martinez-Barricarte R; University of Paris, Imagine Institute, Paris, France.
  • Rosain J; Sidra Medicine, Doha, Qatar.
  • Belkadi A; Sidra Medicine, Doha, Qatar.
  • Breton S; Sidra Medicine, Doha, Qatar.
  • Payne K; Sidra Medicine, Doha, Qatar.
  • Benhsaien I; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
  • Plebani A; University of Paris, Imagine Institute, Paris, France.
  • Lougaris V; St. Giles Laboratory of Human Genetics of Infectious Diseases, The Rockefeller University, New York, New York, USA.
  • Di Santo JP; St. Giles Laboratory of Human Genetics of Infectious Diseases, The Rockefeller University, New York, New York, USA.
  • Neven B; St. Giles Laboratory of Human Genetics of Infectious Diseases, The Rockefeller University, New York, New York, USA.
  • Abel L; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
  • Ma CS; University of Paris, Imagine Institute, Paris, France.
  • Bousfiha AA; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
  • Marr N; University of Paris, Imagine Institute, Paris, France.
  • Bustamante J; Pediatric Radiology, Necker Hospital for Sick Children, Paris, France.
  • Liu K; Garvan Institute, Darlinghurst, New South Wales 2010, Australia.
  • Gros P; King Hassan II University, Casablanca, Morocco.
  • Geissmann F; University of Brescia and ASST-Spedali Civili of Brescia, Brescia, Italy.
  • Tangye SG; University of Brescia and ASST-Spedali Civili of Brescia, Brescia, Italy.
  • Casanova JL; Pasteur Institute, Paris, France.
  • Puel A; University of Paris, Imagine Institute, Paris, France.
J Clin Invest ; 131(17)2021 09 01.
Article in En | MEDLINE | ID: mdl-34623332
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins c-rel / Genes, rel / Primary Immunodeficiency Diseases Limits: Child / Female / Humans Language: En Journal: J Clin Invest Year: 2021 Document type: Article Affiliation country: France Country of publication: United States
Fulltext
Add to My VHL
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins c-rel / Genes, rel / Primary Immunodeficiency Diseases Limits: Child / Female / Humans Language: En Journal: J Clin Invest Year: 2021 Document type: Article Affiliation country: France Country of publication: United States