Psoriasis induced by biological therapy.
Reumatol Clin (Engl Ed)
; 17(8): 437-439, 2021 Oct.
Article
in En
| MEDLINE
| ID: mdl-34625145
ABSTRACT
OBJECTIVE:
To describe a multicentre case series of new onset or worsening of psoriasis in patients treated with biological drugs. MATERIAL ANDMETHODS:
Descriptive study. We reviewed the clinical history of patients with chronic inflammatory disease (CID) treated with biological drugs, who developed new onset or worsening of psoriasis during the follow-up period.RESULTS:
Twenty-six cases of paradoxical psoriasis (PP) were recorded. Ninety-three percent of the patients were treated with anti-TNFα and adalimumab was responsible for 50% of the cases. Only 5 patients had a personal history of psoriasis. The biological drug was discontinued in 13 patients. Lesion recurrence was more frequent when another anti-TNFα was reintroduced.CONCLUSIONS:
The PP is a reversible adverse effect that can be observed in patients exposed to biological drugs, mainly anti-TNFα.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Psoriasis
/
Biological Products
Limits:
Humans
Language:
En
Journal:
Reumatol Clin (Engl Ed)
Year:
2021
Document type:
Article
Publication country:
ES
/
ESPANHA
/
ESPAÑA
/
SPAIN