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Birth weight and diazoxide unresponsiveness strongly predict the likelihood of congenital hyperinsulinism due to a mutation in ABCC8 or KCNJ11.
Hewat, Thomas I; Yau, Daphne; Jerome, Joseph C S; Laver, Thomas W; Houghton, Jayne A L; Shields, Beverley M; Flanagan, Sarah E; Patel, Kashyap A.
Affiliation
  • Hewat TI; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, UK.
  • Yau D; Department of Paediatric Endocrinology, Royal Manchester Children's Hospital, Manchester, UK.
  • Jerome JCS; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, UK.
  • Laver TW; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, UK.
  • Houghton JAL; Royal Devon and Exeter Foundation Hospital, Exeter, UK.
  • Shields BM; National Institute for Health Research Exeter Clinical Research Facility, University of Exeter Medical School, Exeter, UK.
  • Flanagan SE; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, UK.
  • Patel KA; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, UK.
Eur J Endocrinol ; 185(6): 813-818, 2021 Oct 30.
Article in En | MEDLINE | ID: mdl-34633981
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Birth Weight / Potassium Channels, Inwardly Rectifying / Congenital Hyperinsulinism / Diazoxide / KATP Channels / Sulfonylurea Receptors / Mutation Type of study: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male / Newborn Language: En Journal: Eur J Endocrinol Journal subject: ENDOCRINOLOGIA Year: 2021 Document type: Article Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Birth Weight / Potassium Channels, Inwardly Rectifying / Congenital Hyperinsulinism / Diazoxide / KATP Channels / Sulfonylurea Receptors / Mutation Type of study: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male / Newborn Language: En Journal: Eur J Endocrinol Journal subject: ENDOCRINOLOGIA Year: 2021 Document type: Article Country of publication: United kingdom