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TSSK4 upregulation in alveolar epithelial type-II cells facilitates pulmonary fibrosis through HSP90-AKT signaling restriction and AT-II apoptosis.
Chen, Huifang; He, Andong; Li, Haoyang; Chen, Honglv; Xie, Huancheng; Luo, Liping; Huang, Yuyi; Chen, Jiaqian; Guan, Jieying; He, Qiaoling; Ma, Jianjuan; Ou, Changxing; Tao, Ailin; Yan, Jie.
Affiliation
  • Chen H; The Second Affiliated Hospital, The State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Allery & Clinical Immunology, Guangzhou Medical University, Guangzhou, Guangdong, 510260, China.
  • He A; The Second Affiliated Hospital, The State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Allery & Clinical Immunology, Guangzhou Medical University, Guangzhou, Guangdong, 510260, China.
  • Li H; The Second Affiliated Hospital, The State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Allery & Clinical Immunology, Guangzhou Medical University, Guangzhou, Guangdong, 510260, China.
  • Chen H; The Second Affiliated Hospital, The State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Allery & Clinical Immunology, Guangzhou Medical University, Guangzhou, Guangdong, 510260, China.
  • Xie H; The Second Affiliated Hospital, The State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Allery & Clinical Immunology, Guangzhou Medical University, Guangzhou, Guangdong, 510260, China.
  • Luo L; The Second Affiliated Hospital, The State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Allery & Clinical Immunology, Guangzhou Medical University, Guangzhou, Guangdong, 510260, China.
  • Huang Y; The Second Affiliated Hospital, The State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Allery & Clinical Immunology, Guangzhou Medical University, Guangzhou, Guangdong, 510260, China.
  • Chen J; The Second Affiliated Hospital, The State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Allery & Clinical Immunology, Guangzhou Medical University, Guangzhou, Guangdong, 510260, China.
  • Guan J; The Second Affiliated Hospital, The State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Allery & Clinical Immunology, Guangzhou Medical University, Guangzhou, Guangdong, 510260, China.
  • He Q; The Second Affiliated Hospital, The State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Allery & Clinical Immunology, Guangzhou Medical University, Guangzhou, Guangdong, 510260, China.
  • Ma J; The First Affiliated Hospital, The State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, Guangdong, 510120, China.
  • Ou C; Department of Pediatric Hematology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guangxi, 550000, China.
  • Tao A; The First Affiliated Hospital, The State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, Guangdong, 510120, China.
  • Yan J; The Second Affiliated Hospital, The State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Allery & Clinical Immunology, Guangzhou Medical University, Guangzhou, Guangdong, 510260, China.
Cell Death Dis ; 12(10): 938, 2021 10 13.
Article in En | MEDLINE | ID: mdl-34645797
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Up-Regulation / Protein Serine-Threonine Kinases / Apoptosis / HSP90 Heat-Shock Proteins / Proto-Oncogene Proteins c-akt / Idiopathic Pulmonary Fibrosis / Alveolar Epithelial Cells Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cell Death Dis Year: 2021 Document type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Up-Regulation / Protein Serine-Threonine Kinases / Apoptosis / HSP90 Heat-Shock Proteins / Proto-Oncogene Proteins c-akt / Idiopathic Pulmonary Fibrosis / Alveolar Epithelial Cells Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cell Death Dis Year: 2021 Document type: Article Affiliation country: China