p107 mediated mitochondrial function controls muscle stem cell proliferative fates.

Bhattacharya, Debasmita; Shah, Vicky; Oresajo, Oreoluwa; Scimè, Anthony

Bhattacharya, Debasmita; Shah, Vicky; Oresajo, Oreoluwa; Scimè, Anthony.

Affiliation

Bhattacharya D; Stem Cell Research Group, York University, Toronto, ON, M3J 1P3, Canada.
Shah V; Molecular, Cellular and Integrative Physiology, Faculty of Health, York University, Toronto, ON, M3J 1P3, Canada.
Oresajo O; Stem Cell Research Group, York University, Toronto, ON, M3J 1P3, Canada.
Scimè A; Department of Biology, York University, Toronto, ON, M3J 1P3, Canada.

Nat Commun ; 12(1): 5977, 2021 10 13.

Article in En | MEDLINE | ID: mdl-34645816

Subject(s)

Lactate Dehydrogenase 5/genetics; Mitochondria/genetics; Muscle, Skeletal/metabolism; Myoblasts/metabolism; Retinoblastoma-Like Protein p107/genetics; Stem Cells/metabolism; Adenosine Triphosphate/biosynthesis; Animals; Cell Cycle/genetics; Cell Line; Cell Proliferation; DNA, Mitochondrial/genetics; DNA, Mitochondrial/metabolism; Electron Transport Chain Complex Proteins/genetics; Electron Transport Chain Complex Proteins/metabolism; Gene Expression Regulation; Glycolysis; Humans; Lactate Dehydrogenase 5/antagonists & inhibitors; Lactate Dehydrogenase 5/metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria/metabolism; Muscle, Skeletal/cytology; Myoblasts/cytology; Oxidative Phosphorylation; RNA, Small Interfering/genetics; RNA, Small Interfering/metabolism; Retinoblastoma-Like Protein p107/metabolism; Sirtuin 1/genetics; Sirtuin 1/metabolism; Stem Cells/cytology; Transcription, Genetic

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stem Cells / Muscle, Skeletal / Myoblasts / Retinoblastoma-Like Protein p107 / Lactate Dehydrogenase 5 / Mitochondria Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: Canada Country of publication: United kingdom

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