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FABP4 knockdown suppresses inflammation, apoptosis and extracellular matrix degradation in IL-1ß-induced chondrocytes by activating PPARγ to regulate the NF-κB signaling pathway.
Mao, Huajie; Han, Bin; Li, Hao; Tao, Yiqing; Wu, Weigang.
Affiliation
  • Mao H; Department of Orthopedic Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310000, P.R. China.
  • Han B; Department of Orthopedic Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310000, P.R. China.
  • Li H; Department of Orthopedic Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310000, P.R. China.
  • Tao Y; Department of Orthopedic Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310000, P.R. China.
  • Wu W; Department of Orthopedic Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310000, P.R. China.
Mol Med Rep ; 24(6)2021 Dec.
Article in En | MEDLINE | ID: mdl-34651666

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: NF-kappa B / Apoptosis / Chondrocytes / PPAR gamma / Fatty Acid-Binding Proteins / Extracellular Matrix / Inflammation Limits: Animals Language: En Journal: Mol Med Rep Year: 2021 Document type: Article Country of publication: Greece

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: NF-kappa B / Apoptosis / Chondrocytes / PPAR gamma / Fatty Acid-Binding Proteins / Extracellular Matrix / Inflammation Limits: Animals Language: En Journal: Mol Med Rep Year: 2021 Document type: Article Country of publication: Greece