Antibiotic Resistance Mechanisms and Their Transmission in Acinetobacter baumannii.
Adv Exp Med Biol
; 1313: 135-153, 2021.
Article
in En
| MEDLINE
| ID: mdl-34661894
ABSTRACT
The discovery of penicillin over 90 years ago and its subsequent uptake by healthcare systems around the world revolutionised global health. It marked the beginning of a golden age in antibiotic discovery with new antibiotics readily discovered from natural sources and refined into therapies that saved millions of lives. Towards the end of the last century, the rate of discovery slowed to a near standstill. The lack of discovery is compounded by the rapid emergence and spread of bacterial pathogens that exhibit resistance to multiple antibiotic therapies and threaten the sustainability of global healthcare systems. Acinetobacter baumannii is an opportunistic pathogen whose prevalence and impact has grown significantly over the last 20 years. It is recognised as a barometer of the antibiotic resistance crisis due to the diverse array of mechanisms by which it can become resistant.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Acinetobacter baumannii
Type of study:
Risk_factors_studies
Language:
En
Journal:
Adv Exp Med Biol
Year:
2021
Document type:
Article
Affiliation country:
United kingdom