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Higher Order Protein Catenation Leads to an Artificial Antibody with Enhanced Affinity and In Vivo Stability.
Wu, Wen-Hao; Bai, Xilin; Shao, Yu; Yang, Chao; Wei, Jingjing; Wei, Wei; Zhang, Wen-Bin.
Affiliation
  • Wu WH; Beijing National Laboratory for Molecular Sciences, Key Laboratory of Polymer Chemistry & Physics of Ministry of Education, Center for Soft Matter Science and Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, P. R. China.
  • Bai X; Beijing National Laboratory for Molecular Sciences, Key Laboratory of Polymer Chemistry & Physics of Ministry of Education, Center for Soft Matter Science and Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, P. R. China.
  • Shao Y; Beijing National Laboratory for Molecular Sciences, Key Laboratory of Polymer Chemistry & Physics of Ministry of Education, Center for Soft Matter Science and Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, P. R. China.
  • Yang C; College of Chemical and Environmental Engineering, Anyang Institute of Technology, Anyang, Henan 455000, P. R. China.
  • Wei J; College of Chemical and Environmental Engineering, Anyang Institute of Technology, Anyang, Henan 455000, P. R. China.
  • Wei W; State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, P. R. China.
  • Zhang WB; Beijing National Laboratory for Molecular Sciences, Key Laboratory of Polymer Chemistry & Physics of Ministry of Education, Center for Soft Matter Science and Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, P. R. China.
J Am Chem Soc ; 143(43): 18029-18040, 2021 11 03.
Article in En | MEDLINE | ID: mdl-34664942
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Recombinant Fusion Proteins / Tumor Suppressor Protein p53 / Biomimetic Materials / Catenanes / Antibodies Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: J Am Chem Soc Year: 2021 Document type: Article Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Recombinant Fusion Proteins / Tumor Suppressor Protein p53 / Biomimetic Materials / Catenanes / Antibodies Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: J Am Chem Soc Year: 2021 Document type: Article Country of publication: United States