Conjugation of Aztreonam, a Synthetic Monocyclic ß-Lactam Antibiotic, to a Siderophore Mimetic Significantly Expands Activity Against Gram-Negative Bacteria.

Liu, Rui; Miller, Patricia A; Miller, Marvin J

Liu, Rui; Miller, Patricia A; Miller, Marvin J.

Affiliation

Liu R; Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.
Miller PA; Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.
Miller MJ; Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.

ACS Infect Dis ; 7(11): 2979-2986, 2021 11 12.

Article in En | MEDLINE | ID: mdl-34668698

Subject(s)

Aztreonam; Monobactams; Anti-Bacterial Agents/pharmacology; Aztreonam/pharmacology; Gram-Negative Bacteria; Microbial Sensitivity Tests; Monobactams/pharmacology; Siderophores

Key words

MDR bacteria; aztreonam; sideromycin; siderophore conjugate

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aztreonam / Monobactams Language: En Journal: ACS Infect Dis Year: 2021 Document type: Article Affiliation country: United States Country of publication: United States

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