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One dose does not fit all: revising the WHO paediatric dosing tool to include the non-linear effect of body size and maturation.
Denti, Paolo; Wasmann, Roeland E; Francis, Jose; McIlleron, Helen; Sugandhi, Nandita; Cressey, Tim R; Mirochnick, Mark; Capparelli, Edmund V; Penazzato, Martina.
Affiliation
  • Denti P; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Groote Schuur Hospital, Observatory, Cape Town 7925, South Africa. Electronic address: paolo.denti@uct.ac.za.
  • Wasmann RE; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Groote Schuur Hospital, Observatory, Cape Town 7925, South Africa.
  • Francis J; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Groote Schuur Hospital, Observatory, Cape Town 7925, South Africa.
  • McIlleron H; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Groote Schuur Hospital, Observatory, Cape Town 7925, South Africa; Wellcome Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Institute of Infectious Disease and Molecular Medicine, University of Cape
  • Sugandhi N; ICAP, Columbia University, New York, NY, USA.
  • Cressey TR; PHPT/Institut de recherche pour le développement (IRD), MIVEGEC (Maladies Infectieuses et Vecteurs: Ecologie, Génétique, Evolution et Contrôle) Research Unit, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; Department of Molecular & Clinical Pharmacology, Uni
  • Mirochnick M; Boston University School of Medicine, Boston, MA, USA.
  • Capparelli EV; University of California, San Diego Schools of Medicine and Skaggs School of Pharmacy, La Jolla, CA, USA.
  • Penazzato M; World Health Organization, Geneva, Switzerland.
Lancet Child Adolesc Health ; 6(1): 9-10, 2022 01.
Article in En | MEDLINE | ID: mdl-34678142
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pediatrics / Body Weight / HIV Infections / Anti-Retroviral Agents / Dose-Response Relationship, Drug Limits: Adolescent / Child / Humans Language: En Journal: Lancet Child Adolesc Health Year: 2022 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pediatrics / Body Weight / HIV Infections / Anti-Retroviral Agents / Dose-Response Relationship, Drug Limits: Adolescent / Child / Humans Language: En Journal: Lancet Child Adolesc Health Year: 2022 Document type: Article