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ASP-Enzymosomes with Saccharomyces cerevisiae Asparaginase II Expressed in Pichia pastoris: Formulation Design and In Vitro Studies of a Potential Antileukemic Drug.
Girão, Luciana F C; Carvalheiro, Manuela Colla; Ferreira-Silva, Margarida; da Rocha, Surza L G; Perales, Jonas; Martins, M Bárbara F; Ferrara, Maria Antonieta; Bon, Elba P S; Corvo, M Luísa.
Affiliation
  • Girão LFC; Enzyme Technology Laboratory, Department of Biochemistry, Institute of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro 21941-909, RJ, Brazil.
  • Carvalheiro MC; Laboratory of Toxinology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, RJ, Brazil.
  • Ferreira-Silva M; Instituto de Investigação do Medicamento (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisbon, Portugal.
  • da Rocha SLG; Instituto de Investigação do Medicamento (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisbon, Portugal.
  • Perales J; Laboratory of Toxinology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, RJ, Brazil.
  • Martins MBF; Laboratory of Toxinology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, RJ, Brazil.
  • Ferrara MA; Instituto de Investigação do Medicamento (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisbon, Portugal.
  • Bon EPS; Institute of Drug Technology (Farmanguinhos), Oswaldo Cruz Foundation, Rio de Janeiro 21041-250, RJ, Brazil.
  • Corvo ML; Enzyme Technology Laboratory, Department of Biochemistry, Institute of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro 21941-909, RJ, Brazil.
Int J Mol Sci ; 22(20)2021 Oct 15.
Article in En | MEDLINE | ID: mdl-34681778
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asparaginase / Leukemia / Antineoplastic Agents Limits: Humans Language: En Journal: Int J Mol Sci Year: 2021 Document type: Article Affiliation country: Brazil
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asparaginase / Leukemia / Antineoplastic Agents Limits: Humans Language: En Journal: Int J Mol Sci Year: 2021 Document type: Article Affiliation country: Brazil