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Fisetin-induced PTEN expression reverses cellular senescence by inhibiting the mTORC2-Akt Ser473 phosphorylation pathway in vascular smooth muscle cells.
Kim, Seul Gi; Sung, Jin Young; Kim, Jae-Ryong; Choi, Hyoung Chul.
Affiliation
  • Kim SG; Department of Pharmacology, College of Medicine, Yeungnam University, 170 Hyunchung-Ro, Nam-Gu, Daegu 42415, Republic of Korea; Smart-aging Convergence Research Center, College of Medicine, Yeungnam University, 170 Hyunchung-Ro, Nam-Gu, Daegu 42415, Republic of Korea.
  • Sung JY; Department of Pharmacology, College of Medicine, Yeungnam University, 170 Hyunchung-Ro, Nam-Gu, Daegu 42415, Republic of Korea; Smart-aging Convergence Research Center, College of Medicine, Yeungnam University, 170 Hyunchung-Ro, Nam-Gu, Daegu 42415, Republic of Korea.
  • Kim JR; Department of Biochemistry and Molecular Biology, College of Medicine, Yeungnam University, 170 Hyunchung-Ro, Nam-Gu, Daegu 42415, Republic of Korea; Smart-aging Convergence Research Center, College of Medicine, Yeungnam University, 170 Hyunchung-Ro, Nam-Gu, Daegu 42415, Republic of Korea.
  • Choi HC; Department of Pharmacology, College of Medicine, Yeungnam University, 170 Hyunchung-Ro, Nam-Gu, Daegu 42415, Republic of Korea; Smart-aging Convergence Research Center, College of Medicine, Yeungnam University, 170 Hyunchung-Ro, Nam-Gu, Daegu 42415, Republic of Korea. Electronic address: hcchoi@med.
Exp Gerontol ; 156: 111598, 2021 12.
Article in En | MEDLINE | ID: mdl-34695518

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Flavonols / PTEN Phosphohydrolase / Muscle, Smooth, Vascular Limits: Animals Language: En Journal: Exp Gerontol Year: 2021 Document type: Article Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Flavonols / PTEN Phosphohydrolase / Muscle, Smooth, Vascular Limits: Animals Language: En Journal: Exp Gerontol Year: 2021 Document type: Article Country of publication: United kingdom