[Secondary Data for Pharmacoepidemiological Research - Making the Best of It!] / Nutzung von Sekundärdaten für die pharmakoepidemiologische Forschung machen wir das Beste draus!
Gesundheitswesen
; 83(S 02): S69-S76, 2021 Nov.
Article
in De
| MEDLINE
| ID: mdl-34695869
ABSTRACT
Studies using secondary data such as health care claims data are often faced with methodological challenges due to the time-dependence of key quantities or unmeasured confounding. In the present paper, we discuss approaches to avoid or suitably address various sources of potential bias. In particular, we illustrate the target trial principle, marginal structural models, and instrumental variables with examples from the "GePaRD" database. Finally, we discuss the strengths and limitations of record linkage which can sometimes be used to supply missing information.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pharmacoepidemiology
/
Delivery of Health Care
Type of study:
Prognostic_studies
Aspects:
Determinantes_sociais_saude
Country/Region as subject:
Europa
Language:
De
Journal:
Gesundheitswesen
Journal subject:
SAUDE PUBLICA
Year:
2021
Document type:
Article