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A live measles-vectored COVID-19 vaccine induces strong immunity and protection from SARS-CoV-2 challenge in mice and hamsters.
Frantz, Phanramphoei N; Barinov, Aleksandr; Ruffié, Claude; Combredet, Chantal; Najburg, Valérie; de Melo, Guilherme Dias; Larrous, Florence; Kergoat, Lauriane; Teeravechyan, Samaporn; Jongkaewwattana, Anan; Billon-Denis, Emmanuelle; Tournier, Jean-Nicolas; Prot, Matthieu; Levillayer, Laurine; Conquet, Laurine; Montagutelli, Xavier; Tichit, Magali; Hardy, David; Fernandes, Priyanka; Strick-Marchand, Hélène; Di Santo, James; Simon-Lorière, Etienne; Bourhy, Hervé; Tangy, Frédéric.
Affiliation
  • Frantz PN; Institut Pasteur, Université de Paris, Innovation Lab: Vaccines, Paris, France.
  • Barinov A; National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency, Virology and Cell Technology Laboratory, Pathumthani, Thailand.
  • Ruffié C; Institut Pasteur, Université de Paris, Innovation Lab: Vaccines, Paris, France.
  • Combredet C; Viroxis, Paris, France.
  • Najburg V; Institut Pasteur, Université de Paris, Innovation Lab: Vaccines, Paris, France.
  • de Melo GD; Institut Pasteur, Université de Paris, Innovation Lab: Vaccines, Paris, France.
  • Larrous F; Institut Pasteur, Université de Paris, Innovation Lab: Vaccines, Paris, France.
  • Kergoat L; Institut Pasteur, Université de Paris, Lyssavirus Epidemiology and Neuropathology Unit, Paris, France.
  • Teeravechyan S; Institut Pasteur, Université de Paris, Lyssavirus Epidemiology and Neuropathology Unit, Paris, France.
  • Jongkaewwattana A; Institut Pasteur, Université de Paris, Lyssavirus Epidemiology and Neuropathology Unit, Paris, France.
  • Billon-Denis E; National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency, Virology and Cell Technology Laboratory, Pathumthani, Thailand.
  • Tournier JN; National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency, Virology and Cell Technology Laboratory, Pathumthani, Thailand.
  • Prot M; Armed Forces Biomedical Research Institute (IRBA), Microbiology and infectious diseases department, Brétgny-sur-Orge, France.
  • Levillayer L; Armed Forces Biomedical Research Institute (IRBA), Microbiology and infectious diseases department, Brétgny-sur-Orge, France.
  • Conquet L; Institut Pasteur, Université de Paris, Evolutionary Genomics of RNA viruses unit, Paris, France.
  • Montagutelli X; Institut Pasteur, Université de Paris, Evolutionary Genomics of RNA viruses unit, Paris, France.
  • Tichit M; Institut Pasteur, Université de Paris, Laboratory of Mouse Genetics, Paris, France.
  • Hardy D; Institut Pasteur, Université de Paris, Laboratory of Mouse Genetics, Paris, France.
  • Fernandes P; Institut Pasteur, Université de Paris, Experimental Neuropathology unit, Paris, France.
  • Strick-Marchand H; Institut Pasteur, Université de Paris, Experimental Neuropathology unit, Paris, France.
  • Di Santo J; Institut Pasteur, Université de Paris, INSERM U1223, Innate Immunity unit, Paris, France.
  • Simon-Lorière E; Institut Pasteur, Université de Paris, INSERM U1223, Innate Immunity unit, Paris, France.
  • Bourhy H; Institut Pasteur, Université de Paris, INSERM U1223, Innate Immunity unit, Paris, France.
  • Tangy F; Institut Pasteur, Université de Paris, Evolutionary Genomics of RNA viruses unit, Paris, France.
Nat Commun ; 12(1): 6277, 2021 11 01.
Article in En | MEDLINE | ID: mdl-34725327
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: COVID-19 Vaccines / Genetic Vectors / COVID-19 / Immunity Type of study: Prognostic_studies Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: France Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: COVID-19 Vaccines / Genetic Vectors / COVID-19 / Immunity Type of study: Prognostic_studies Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: France Country of publication: United kingdom