Prophylactic use of proton pump inhibitors post-cardiac surgery.
Br J Hosp Med (Lond)
; 82(10): 1-7, 2021 Oct 02.
Article
in En
| MEDLINE
| ID: mdl-34726935
ABSTRACT
AIMS/BACKGROUND:
Gastrointestinal bleeding significantly increases morbidity and mortality rates postoperatively in patients undergoing cardiac surgery. The prophylactic prescribing of proton pump inhibitors post-cardiac surgery is currently a class IIa recommendation of the European Association of Cardio-Thoracic Surgery.METHOD:
A retrospective review of patients who underwent cardiac surgery between July and December 2019 in the authors' hospital was carried out, using discharge summaries. New treatment charts were introduced with a pre-printed proton pump inhibitor included in the 'regular medication' section of the treatment chart and two reaudits were performed using the same methodology.RESULTS:
Before the intervention, 47% were prescribed omeprazole postoperatively, compared to 74% (P<0.001) and 66% (P=0.008) in the first and second reaudits respectively. Gastrointestinal bleeding was more common pre-intervention (4% vs 1% respectively; P=0.10).CONCLUSIONS:
This intervention resulted in a statistically significant improvement in the prescription of postoperative omeprazole and a decrease in gastrointestinal bleeds. However, other risk factors such as diabetes mellitus, arteriosclerosis and procedure urgency may have contributed to the absence of statistical significance in the latter.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Thoracic Surgery
/
Cardiac Surgical Procedures
Type of study:
Guideline
/
Observational_studies
/
Risk_factors_studies
Limits:
Humans
Language:
En
Journal:
Br J Hosp Med (Lond)
Journal subject:
HOSPITAIS
/
MEDICINA
Year:
2021
Document type:
Article
Affiliation country:
Malta