Amiodarone pulmonary toxicity. Clinical, cytologic and ultrastructural findings.
Acta Cytol
; 31(3): 357-61, 1987.
Article
in En
| MEDLINE
| ID: mdl-3473872
ABSTRACT
Amiodarone, a new antiarrhythmic drug, may produce severe and potentially lethal pulmonary toxicity. A case is presented of a patient on amiodarone therapy who presented with recurrent pleural effusions and subsequently developed pulmonary infiltrates. The diagnosis of lung toxicity was documented by the cytologic examination of the pleural effusions and the bronchial washings. It was further supported by the ultrastructural demonstration of the characteristic cytoplasmic osmiophilic lamellar inclusions in the foamy macrophages. We conclude that cytologic and ultrastructural examinations of bronchial lavage cells are extremely helpful in the diagnosis of amiodarone-induced pulmonary toxicity.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pleural Effusion
/
Amiodarone
Type of study:
Diagnostic_studies
Limits:
Aged
/
Female
/
Humans
Language:
En
Journal:
Acta Cytol
Year:
1987
Document type:
Article