Co-culture of mesenchymal stem cell spheres with hematopoietic stem cells under hypoxia: a cost-effective method to maintain self-renewal and homing marker expression.

Amiri, Fatemeh; Kiani, Ali Asghar; Bahadori, Marzie; Roudkenar, Mehryar Habibi

Amiri, Fatemeh; Kiani, Ali Asghar; Bahadori, Marzie; Roudkenar, Mehryar Habibi.

Affiliation

Amiri F; Department of Medical Laboratory Sciences, School of Para Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Kiani AA; Department of Hematology and Blood Transfusion, Lorestan University of Medical Sciences, Khorramabad, Lorestan, Iran.
Bahadori M; Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran.
Roudkenar MH; Cardiovascular Diseases Research Center, Department of Cardiology, Heshmat Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran. roudkenar@gums.ac.ir.

Mol Biol Rep ; 49(2): 931-941, 2022 Feb.

Article in En | MEDLINE | ID: mdl-34741711

Subject(s)

Coculture Techniques/methods; Hematopoietic Stem Cells/metabolism; Mesenchymal Stem Cells/metabolism; Antigens, CD34/metabolism; Cell Culture Techniques; Cell Differentiation; Cell Hypoxia/physiology; Cell Proliferation; Cells, Cultured; Coculture Techniques/economics; Cost-Benefit Analysis; Cytokines/metabolism; Fetal Blood/cytology; Humans; Receptors, CXCR4

Key words

Co-culture; Endothelial protein C receptor; Hematopoietic stem cell; Hypoxia; Mesenchymal stem cell; Sphere

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hematopoietic Stem Cells / Coculture Techniques / Mesenchymal Stem Cells Type of study: Health_economic_evaluation Limits: Humans Language: En Journal: Mol Biol Rep Year: 2022 Document type: Article Affiliation country: Iran Country of publication: Netherlands

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