GLI1-targeting drugs induce replication stress and homologous recombination deficiency and synergize with PARP-targeted therapies in triple negative breast cancer cells.
Biochim Biophys Acta Mol Basis Dis
; 1868(2): 166300, 2022 02 01.
Article
in En
| MEDLINE
| ID: mdl-34748904
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pyridines
/
Pyrimidines
/
DNA Replication
/
Drug Synergism
/
Homologous Recombination
/
Triple Negative Breast Neoplasms
/
Poly(ADP-ribose) Polymerase Inhibitors
/
Zinc Finger Protein GLI1
Type of study:
Prognostic_studies
Limits:
Humans
Language:
En
Journal:
Biochim Biophys Acta Mol Basis Dis
Year:
2022
Document type:
Article