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Coagulation and immunity: Caught in the fibrin web.
Sozmen, Elif G; Akassoglou, Katerina.
Affiliation
  • Sozmen EG; Center for Neurovascular Brain Immunology at Gladstone and UCSF, San Francisco, CA 94158, USA; Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA 94158, USA; Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, CA 94158, USA.
  • Akassoglou K; Center for Neurovascular Brain Immunology at Gladstone and UCSF, San Francisco, CA 94158, USA; Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA 94158, USA; Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, CA 94158, USA. Electronic address: kakassoglou@gladstone.ucsf.edu.
Immunity ; 54(11): 2439-2441, 2021 11 09.
Article in En | MEDLINE | ID: mdl-34758333
ABSTRACT
In this issue of Immunity, Vega-Pérez et al. (2021) reveal the formation of a dynamic multicellular aggregate within a fibrin scaffold consisting of large peritoneal macrophages, B1 cells, neutrophils, and monocytes during antibacterial immunity in the peritoneum. Anticoagulants targeting thrombin or peritoneal macrophage depletion by clodronate impaired efficient control of E. coli infection.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Fibrin / Escherichia coli Limits: Animals Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2021 Document type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Fibrin / Escherichia coli Limits: Animals Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2021 Document type: Article Affiliation country: United States