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Preclinical Characterization of a Next-Generation Brain Permeable, Paradox Breaker BRAF Inhibitor.
Wichmann, Jürgen; Rynn, Caroline; Friess, Thomas; Petrig-Schaffland, Jeannine; Kornacker, Martin; Handl, Cornelia; Emmenegger, Jasmin; Eckmann, Jan; Herting, Frank; Frances, Nicolas; Hunziker, Daniel; Krummenacher, Daniela; Rüttinger, Dominik; Ribeiro, Alison; Bacac, Marina; Brigo, Alessandro; Hewings, David S; Dummer, Reinhard; Levesque, Mitchell P; Schnetzler, Gabriel; Martoglio, Bruno; Bischoff, James R; Pettazzoni, Piergiorgio.
Affiliation
  • Wichmann J; Roche Pharma Research & Early Development pRED, Roche Innovation Center Basel, Switzerland.
  • Rynn C; Roche Pharma Research & Early Development pRED, Roche Innovation Center Basel, Switzerland.
  • Friess T; Roche Pharma Research & Early Development pRED, Roche Innovation Center Munich, Penzberg, Germany.
  • Petrig-Schaffland J; Roche Pharma Research & Early Development pRED, Roche Innovation Center Basel, Switzerland.
  • Kornacker M; Roche Pharma Research & Early Development pRED, Roche Innovation Center Basel, Switzerland.
  • Handl C; Roche Pharma Research & Early Development pRED, Roche Innovation Center Basel, Switzerland.
  • Emmenegger J; Roche Pharma Research & Early Development pRED, Roche Innovation Center Basel, Switzerland.
  • Eckmann J; Roche Pharma Research & Early Development pRED, Roche Innovation Center Munich, Penzberg, Germany.
  • Herting F; Roche Pharma Research & Early Development pRED, Roche Innovation Center Munich, Penzberg, Germany.
  • Frances N; Roche Pharma Research & Early Development pRED, Roche Innovation Center Basel, Switzerland.
  • Hunziker D; Roche Pharma Research & Early Development pRED, Roche Innovation Center Basel, Switzerland.
  • Krummenacher D; Roche Pharma Research & Early Development pRED, Roche Innovation Center Basel, Switzerland.
  • Rüttinger D; Roche Pharma Research & Early Development pRED, Roche Innovation Center Munich, Penzberg, Germany.
  • Ribeiro A; Roche Pharma Research & Early Development pRED, Roche Innovation Center Zurich, Schlieren Switzerland.
  • Bacac M; Roche Pharma Research & Early Development pRED, Roche Innovation Center Zurich, Schlieren Switzerland.
  • Brigo A; Roche Pharma Research & Early Development pRED, Roche Innovation Center Basel, Switzerland.
  • Hewings DS; Roche Pharma Research & Early Development pRED, Roche Innovation Center Basel, Switzerland.
  • Dummer R; Dermatology of Department, University of Zurich, University Hospital Zurich, Zurich, Switzerland.
  • Levesque MP; Dermatology of Department, University of Zurich, University Hospital Zurich, Zurich, Switzerland.
  • Schnetzler G; Roche Pharma Research & Early Development pRED, Roche Innovation Center Basel, Switzerland.
  • Martoglio B; Roche Pharma Research & Early Development pRED, Roche Innovation Center Basel, Switzerland.
  • Bischoff JR; Roche Pharma Research & Early Development pRED, Roche Innovation Center Basel, Switzerland.
  • Pettazzoni P; Roche Pharma Research & Early Development pRED, Roche Innovation Center Basel, Switzerland.
Clin Cancer Res ; 28(4): 770-780, 2022 02 15.
Article in En | MEDLINE | ID: mdl-34782366
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins B-raf / Melanoma Limits: Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2022 Document type: Article Affiliation country: Switzerland Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins B-raf / Melanoma Limits: Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2022 Document type: Article Affiliation country: Switzerland Country of publication: United States