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Targeting a Novel KRAS Binding Site: Application of One-Component Stapling of Small (5-6-mer) Peptides.
Fumagalli, Gabriele; Carbajo, Rodrigo J; Nissink, J Willem M; Tart, Jonathan; Dou, Rongxuan; Thomas, Andrew P; Spring, David R.
Affiliation
  • Fumagalli G; Department of Chemistry, Cambridge University, Lensfield Road, Cambridge CB2 1EW, U.K.
  • Carbajo RJ; Chemistry, Oncology R&D, AstraZeneca, Cambridge CB4 0WG, U.K.
  • Nissink JWM; Chemistry, Oncology R&D, AstraZeneca, Cambridge CB4 0WG, U.K.
  • Tart J; Chemistry, Oncology R&D, AstraZeneca, Cambridge CB4 0WG, U.K.
  • Dou R; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge CB4 0WG, U.K.
  • Thomas AP; Department of Chemistry, Cambridge University, Lensfield Road, Cambridge CB2 1EW, U.K.
  • Spring DR; Chemistry, Oncology R&D, AstraZeneca, Cambridge CB4 0WG, U.K.
J Med Chem ; 64(23): 17287-17303, 2021 12 09.
Article in En | MEDLINE | ID: mdl-34787423
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Proto-Oncogene Proteins p21(ras) Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2021 Document type: Article Affiliation country: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Proto-Oncogene Proteins p21(ras) Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2021 Document type: Article Affiliation country: United kingdom