Trimethylamine N-oxide promotes hyperlipidemia acute pancreatitis via inflammatory response.

Yang, Guodong; Zhang, Xiaoying

Yang, Guodong; Zhang, Xiaoying.

Affiliation

Yang G; Department of Gastroenterology and Hepatology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, China.
Zhang X; School of Basic Medicine, North Sichuan Medical College, Nanchong, Sichuan 637000, China.

Can J Physiol Pharmacol ; 100(1): 61-67, 2022 Jan.

Article in En | MEDLINE | ID: mdl-34793682

Subject(s)

Hyperlipidemias/etiology; Methylamines/adverse effects; Pancreatitis/etiology; ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism; Animals; Cytokines/metabolism; Disease Models, Animal; Gastrointestinal Microbiome/physiology; Hexanols/pharmacology; Hexanols/therapeutic use; Hyperlipidemias/drug therapy; Hyperlipidemias/metabolism; Inflammation; Inflammation Mediators/metabolism; Lipid Metabolism/drug effects; Male; Methylamines/metabolism; Mice, Inbred C57BL; Molecular Targeted Therapy; Pancreatitis/drug therapy; Pancreatitis/metabolism; Signal Transduction/drug effects; Toll-Like Receptors/metabolism

Key words

N-oxyde de triméthylamine; TLR/p65; Trimethylamine N-oxide; gut microbiota; hyperlipidemia acute pancreatitis; inflammatory response; microbiote intestinal; pancréatite aiguë liée à l'hyperlipidémie; réaction inflammatoire

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatitis / Hyperlipidemias / Methylamines Limits: Animals Language: En Journal: Can J Physiol Pharmacol Year: 2022 Document type: Article Affiliation country: China Country of publication: Canada

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