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Temporary mechanical circulatory support in cardiogenic shock.
Obradovic, Danilo; Freund, Anne; Feistritzer, Hans-Josef; Sulimov, Dmitry; Loncar, Goran; Abdel-Wahab, Mohamed; Zeymer, Uwe; Desch, Steffen; Thiele, Holger.
Affiliation
  • Obradovic D; Heart Center Leipzig at University of Leipzig and Leipzig Heart Institute, Leipzig, Germany.
  • Freund A; Heart Center Leipzig at University of Leipzig and Leipzig Heart Institute, Leipzig, Germany.
  • Feistritzer HJ; Heart Center Leipzig at University of Leipzig and Leipzig Heart Institute, Leipzig, Germany.
  • Sulimov D; Heart Center Leipzig at University of Leipzig and Leipzig Heart Institute, Leipzig, Germany.
  • Loncar G; Institute for Cardiovascular Diseases 'Dedinje', University of Belgrade, Belgrade, Serbia; Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
  • Abdel-Wahab M; Heart Center Leipzig at University of Leipzig and Leipzig Heart Institute, Leipzig, Germany.
  • Zeymer U; Institut für Herzinfarktforschung, Ludwigshafen, Germany.
  • Desch S; Heart Center Leipzig at University of Leipzig and Leipzig Heart Institute, Leipzig, Germany.
  • Thiele H; Heart Center Leipzig at University of Leipzig and Leipzig Heart Institute, Leipzig, Germany. Electronic address: holger.thiele@medizin.uni-leipzig.de.
Prog Cardiovasc Dis ; 69: 35-46, 2021.
Article in En | MEDLINE | ID: mdl-34801576
Cardiogenic shock (CS) represents one of the foremost concerns in the field of acute cardiovascular medicine. Despite major advances in treatment, mortality of CS remains high. International societies recommend the development of expert CS centers with standardized protocols for CS diagnosis and treatment. In these terms, devices for temporary mechanical circulatory support (MCS) can be used to support the compromised circulation and could improve clinical outcome in selected patient populations presenting with CS. In the past years, we have witnessed an immense increase in the utilization of MCS devices to improve the clinical problem of low cardiac output. Although some treatment guidelines include the use of temporary MCS up to now no large randomized controlled trial confirmed a reduction in mortality in CS patients after MCS and additional research evidence is necessary to fully comprehend the clinical value of MCS in CS. In this article, we provide an overview of the most important diagnostic and therapeutic modalities in CS with the main focus on contemporary MCS devices, current state of art and scientific evidence for its clinical application and outline directions of future research efforts.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Extracorporeal Membrane Oxygenation / Heart-Assist Devices Type of study: Clinical_trials / Diagnostic_studies / Guideline Limits: Humans Language: En Journal: Prog Cardiovasc Dis Year: 2021 Document type: Article Affiliation country: Germany Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Extracorporeal Membrane Oxygenation / Heart-Assist Devices Type of study: Clinical_trials / Diagnostic_studies / Guideline Limits: Humans Language: En Journal: Prog Cardiovasc Dis Year: 2021 Document type: Article Affiliation country: Germany Country of publication: United States