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Orotic acid protects pancreatic ß cell by p53 inactivation in diabetic mouse model.
Fushimura, Yohei; Hoshino, Atsushi; Furukawa, Satoru; Nakagawa, Takashi; Hino, Tomohiro; Taminishi, Shunta; Minami, Yoshito; Urata, Ryota; Iwai-Kanai, Eri; Matoba, Satoaki.
Affiliation
  • Fushimura Y; Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
  • Hoshino A; Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
  • Furukawa S; Furukawa Research Office Co. Ltd., Tokyo, 157-0066, Japan.
  • Nakagawa T; Department of Molecular and Medical Pharmacology Faculty of Medicine, University of Toyama, Toyama, 930-0194, Japan.
  • Hino T; Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
  • Taminishi S; Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
  • Minami Y; Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
  • Urata R; Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
  • Iwai-Kanai E; Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan; Faculty of Health Care, Tenri Health Care University, Nara, 632-0018, Japan.
  • Matoba S; Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan. Electronic address: matoba@koto.kpu-m.ac.jp.
Biochem Biophys Res Commun ; 585: 191-195, 2021 12 31.
Article in En | MEDLINE | ID: mdl-34813979
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Orotic Acid / Tumor Suppressor Protein p53 / Diabetes Mellitus, Type 2 / Disease Models, Animal / Insulin-Secreting Cells Limits: Animals / Humans / Male Language: En Journal: Biochem Biophys Res Commun Year: 2021 Document type: Article Affiliation country: Japan Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Orotic Acid / Tumor Suppressor Protein p53 / Diabetes Mellitus, Type 2 / Disease Models, Animal / Insulin-Secreting Cells Limits: Animals / Humans / Male Language: En Journal: Biochem Biophys Res Commun Year: 2021 Document type: Article Affiliation country: Japan Country of publication: United States