Cortistatin regulates fibrosis and myofibroblast activation in experimental hepatotoxic- and cholestatic-induced liver injury.

Benitez, Raquel; Caro, Marta; Andres-Leon, Eduardo; O'Valle, Francisco; Delgado, Mario

Benitez, Raquel; Caro, Marta; Andres-Leon, Eduardo; O'Valle, Francisco; Delgado, Mario.

Affiliation

Benitez R; Department of Immunology and Cell Biology, Institute of Parasitology and Biomedicine Lopez-Neyra, Granada, Spain.
Caro M; Department of Immunology and Cell Biology, Institute of Parasitology and Biomedicine Lopez-Neyra, Granada, Spain.
Andres-Leon E; Department of Immunology and Cell Biology, Institute of Parasitology and Biomedicine Lopez-Neyra, Granada, Spain.
O'Valle F; Department of Pathology, School of Medicine, IBIMER and IBS-Granada, University of Granada, Granada, Spain.
Delgado M; Department of Immunology and Cell Biology, Institute of Parasitology and Biomedicine Lopez-Neyra, Granada, Spain.

Br J Pharmacol ; 179(10): 2275-2296, 2022 05.

Article in En | MEDLINE | ID: mdl-34821378

Subject(s)

Chemical and Drug Induced Liver Injury, Chronic; Neuropeptides; Animals; Chemical and Drug Induced Liver Injury, Chronic/metabolism; Chemical and Drug Induced Liver Injury, Chronic/pathology; Fibrosis; Hepatic Stellate Cells/metabolism; Liver/metabolism; Liver Cirrhosis/metabolism; Mice; Myofibroblasts/metabolism; Neuropeptides/metabolism

Key words

Kupffer cells; bile duct ligation; contractile fibres; hepatic stellate cell; neuropeptide; periportal fibroblast

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neuropeptides / Chemical and Drug Induced Liver Injury, Chronic Type of study: Prognostic_studies Limits: Animals Language: En Journal: Br J Pharmacol Year: 2022 Document type: Article Affiliation country: Spain Country of publication: United kingdom

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