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Peripheral venous catheter colonization after skin disinfection with 0.5% aqueous sodium hypochlorite, preceded or not by one application of 70% ethanol (DACLEAN): a single-centre, randomized, open-label, pilot study.
Drugeon, B; Pichon, M; Marjanovic, N; Mousse, S; Seguin, S; Raynaud, C; Rahoui, A; Frasca, D; Mimoz, O; Guenezan, J.
Affiliation
  • Drugeon B; CHU de Poitiers, Service des Urgences et SAMU 86, Poitiers, France.
  • Pichon M; CHU de Poitiers, Département des agents infectieux, Laboratoire de Bactériologie-Hygiène, Poitiers, France; Université de Poitiers, INSERM U1070, Pharmacologie des Agents Anti-Infectieux et Résistance (PHAR2), Poitiers, France.
  • Marjanovic N; CHU de Poitiers, Service des Urgences et SAMU 86, Poitiers, France.
  • Mousse S; CHU de Poitiers, Service des Urgences et SAMU 86, Poitiers, France.
  • Seguin S; CHU de Poitiers, Service des Urgences et SAMU 86, Poitiers, France.
  • Raynaud C; CHU de Poitiers, Service des Urgences et SAMU 86, Poitiers, France; Université de Poitiers, UFR de Médecine-Pharmacie, Poitiers, France.
  • Rahoui A; CHU de Poitiers, Service des Urgences et SAMU 86, Poitiers, France; Université de Poitiers, UFR de Médecine-Pharmacie, Poitiers, France.
  • Frasca D; CHU de Poitiers, Service des Urgences et SAMU 86, Poitiers, France; Université de Nantes, INSERM U1246, Methods in Patient-centered Outcomes and Health Research - SPHERE, Nantes, France.
  • Mimoz O; CHU de Poitiers, Service des Urgences et SAMU 86, Poitiers, France; Université de Poitiers, INSERM U1070, Pharmacologie des Agents Anti-Infectieux et Résistance (PHAR2), Poitiers, France; Université de Poitiers, UFR de Médecine-Pharmacie, Poitiers, France. Electronic address: Olivier.MIMOZ@chu-poiti
  • Guenezan J; CHU de Poitiers, Service des Urgences et SAMU 86, Poitiers, France.
J Hosp Infect ; 120: 123-126, 2022 Feb.
Article in En | MEDLINE | ID: mdl-34822950
ABSTRACT
Few data are available on the efficacy of 0.5% aqueous sodium hypochlorite (SH) for skin disinfection before peripheral catheter insertion. A total of 239 patients were randomly assigned to either one application of SH alone or one application of SH preceded by one application of 70% ethanol (ET-SH). Catheter colonization, defined as a catheter tip culture growing >1000 cfu of a micro-organism per millilitre, occurred in 29 patients (33% of 89 colonizations per 1000 catheter-days) in the SH group and in 31 patients (33% of 126 colonizations per 1000 catheter-days) in the ET-SH group.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Catheterization, Central Venous / Anti-Infective Agents, Local Type of study: Clinical_trials Limits: Humans Language: En Journal: J Hosp Infect Year: 2022 Document type: Article Affiliation country: France
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Catheterization, Central Venous / Anti-Infective Agents, Local Type of study: Clinical_trials Limits: Humans Language: En Journal: J Hosp Infect Year: 2022 Document type: Article Affiliation country: France