Mitochondrial dysfunction as a trigger of programmed axon death.

Merlini, Elisa; Coleman, Michael P; Loreto, Andrea

Merlini, Elisa; Coleman, Michael P; Loreto, Andrea.

Affiliation

Merlini E; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Forvie Site, Cambridge CB2 0PY, UK.
Coleman MP; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Forvie Site, Cambridge CB2 0PY, UK.
Loreto A; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Forvie Site, Cambridge CB2 0PY, UK. Electronic address: al850@cam.ac.uk.

Trends Neurosci ; 45(1): 53-63, 2022 01.

Article in En | MEDLINE | ID: mdl-34852932

Subject(s)

Peripheral Nervous System Diseases; Armadillo Domain Proteins/metabolism; Axons/pathology; Cytoskeletal Proteins/metabolism; Humans; Mitochondria/metabolism; Peripheral Nervous System Diseases/metabolism; Peripheral Nervous System Diseases/pathology; Wallerian Degeneration/metabolism; Wallerian Degeneration/pathology

Key words

Parkinson's disease; SARM1; Wallerian degeneration; axon degeneration; mitochondrial dysfunction; programmed axon death

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peripheral Nervous System Diseases Limits: Humans Language: En Journal: Trends Neurosci Year: 2022 Document type: Article Affiliation country: United kingdom

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