[Depression in men with testosterone deficiency]. / Depressiya u muzhchin s defitsitom testosterona.

ABSTRACT

OBJECTIVE: Clinical assessment of depression in men with testosterone deficiency to improve differential diagnosis of this type of depression. MATERIAL AND METHODS: Thirty-seven men (mean age 50.1±9.08 years) with depressive episode and testosterone level ≤12.1 nmol/l were included in the main group. Depressive episode was diagnosed based on ICD-10 criteria (F-32). Additional assessment of physical and psychometrics parameters was evaluated. Forty men (mean age 42.3±10.53 years) with depression based on ICD-10 criteria (F32, F33) and testosterone level >12.1 nmol/l were included in the comparison group. RESULTS: Symptoms of depression in men with testosterone deficiency were less severe and led to less functional disturbance. There were some clinical differences in symptoms and syndromes. Single-episode course with manifestation at a later age was more typical for the main group while the comparison group was mostly characterized by recurrent episodes manifesting at an earlier age. CONCLUSION: Depression in men with testosterone deficiency has a number of differences that must be taken into account when diagnosing and choosing treatment tactics.