Oroxin B Attenuates Ovariectomy-Induced Bone Loss by Suppressing Osteoclast Formation and Activity.

Huang, Jun-Ming; Wang, Chen-Zhong; Lu, Shun-Yi; Wang, Zhe; Yan, Zuo-Qin

Huang, Jun-Ming; Wang, Chen-Zhong; Lu, Shun-Yi; Wang, Zhe; Yan, Zuo-Qin.

Affiliation

Huang JM; Department of Orthopaedics, Zhongshan Hospital, Fudan University, Shanghai, 200032, People's Republic of China.
Wang CZ; Department of Orthopaedics, Zhongshan Hospital, Fudan University, Shanghai, 200032, People's Republic of China.
Lu SY; Department of Orthopaedics, Zhongshan Hospital, Fudan University, Shanghai, 200032, People's Republic of China.
Wang Z; Department of Orthopaedics, Zhongshan Hospital, Fudan University, Shanghai, 200032, People's Republic of China.
Yan ZQ; Department of Orthopaedics, Zhongshan Hospital, Fudan University, Shanghai, 200032, People's Republic of China.

Drug Des Devel Ther ; 15: 4811-4825, 2021.

Article in En | MEDLINE | ID: mdl-34876805

Subject(s)

Bone Resorption/drug therapy; Disaccharides/pharmacology; Flavones/pharmacology; Osteoclasts/drug effects; Ovariectomy; Animals; Cells, Cultured; Male; Mice; Mice, Inbred C57BL; Osteoclasts/metabolism; Osteogenesis/drug effects

Key words

MAPK; NF-κB; Oroxin B; RANKL; osteoclast; osteoporosis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoclasts / Bone Resorption / Ovariectomy / Flavones / Disaccharides Type of study: Prognostic_studies Limits: Animals Language: En Journal: Drug Des Devel Ther Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2021 Document type: Article Country of publication: New Zealand

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