The Development of BTK Inhibitors: A Five-Year Update.

Tasso, Bruno; Spallarossa, Andrea; Russo, Eleonora; Brullo, Chiara

Tasso, Bruno; Spallarossa, Andrea; Russo, Eleonora; Brullo, Chiara.

Affiliation

Tasso B; Department of Pharmacy, University of Genova, Viale Benedetto XV 3, 16132 Genova, Italy.
Spallarossa A; Department of Pharmacy, University of Genova, Viale Benedetto XV 3, 16132 Genova, Italy.
Russo E; Department of Pharmacy, University of Genova, Viale Benedetto XV 3, 16132 Genova, Italy.
Brullo C; Department of Pharmacy, University of Genova, Viale Benedetto XV 3, 16132 Genova, Italy.

Molecules ; 26(23)2021 Dec 06.

Article in En | MEDLINE | ID: mdl-34885993

Subject(s)

Agammaglobulinaemia Tyrosine Kinase/antagonists & inhibitors; Agammaglobulinaemia Tyrosine Kinase/metabolism; Autoimmune Diseases/drug therapy; Autoimmune Diseases/metabolism; Neoplasms/drug therapy; Neoplasms/metabolism; Protein Kinase Inhibitors/therapeutic use; Agammaglobulinaemia Tyrosine Kinase/chemistry; Agammaglobulinaemia Tyrosine Kinase/classification; Animals; B-Lymphocytes/metabolism; Humans; Inhibitory Concentration 50; Treatment Outcome

Key words

(ir)reversible inhibitors; B-cell malignancies; Bruton's kinase; autoimmune diseases; medicinal chemistry; small molecules

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autoimmune Diseases / Protein Kinase Inhibitors / Agammaglobulinaemia Tyrosine Kinase / Neoplasms Limits: Animals / Humans Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2021 Document type: Article Affiliation country: Italy

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google