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Biphasic activation of ß-arrestin 1 upon interaction with a GPCR revealed by methyl-TROSY NMR.
Shiraishi, Yutaro; Kofuku, Yutaka; Ueda, Takumi; Pandey, Shubhi; Dwivedi-Agnihotri, Hemlata; Shukla, Arun K; Shimada, Ichio.
Affiliation
  • Shiraishi Y; Laboratory for Dynamic Structure of Biomolecules, RIKEN Center for Biosystems Dynamics Research (BDR), 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan.
  • Kofuku Y; Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo, 113-0033, Japan.
  • Ueda T; Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo, 113-0033, Japan.
  • Pandey S; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.
  • Dwivedi-Agnihotri H; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.
  • Shukla AK; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.
  • Shimada I; Laboratory for Dynamic Structure of Biomolecules, RIKEN Center for Biosystems Dynamics Research (BDR), 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan. ichio.shimada@riken.jp.
Nat Commun ; 12(1): 7158, 2021 12 09.
Article in En | MEDLINE | ID: mdl-34887409

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, G-Protein-Coupled / Beta-Arrestin 1 Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: Japan Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, G-Protein-Coupled / Beta-Arrestin 1 Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: Japan Country of publication: United kingdom