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A dose-finding design for dual-agent trials with patient-specific doses for one agent with application to an opiate detoxification trial.
Mozgunov, Pavel; Cro, Suzie; Lingford-Hughes, Anne; Paterson, Louise M; Jaki, Thomas.
Affiliation
  • Mozgunov P; MRC Biostatistics Unit, University of Cambridge, Cambridge, UK.
  • Cro S; Imperial Clinical Trials Unit, School of Public Health, Imperial College, London, UK.
  • Lingford-Hughes A; Division of Psychiatry, Department of Brain Sciences, Imperial College, London, UK.
  • Paterson LM; Division of Psychiatry, Department of Brain Sciences, Imperial College, London, UK.
  • Jaki T; MRC Biostatistics Unit, University of Cambridge, Cambridge, UK.
Pharm Stat ; 21(2): 476-495, 2022 03.
Article in En | MEDLINE | ID: mdl-34891221

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Opiate Alkaloids / Neoplasms Type of study: Diagnostic_studies / Guideline / Prognostic_studies Limits: Humans Language: En Journal: Pharm Stat Journal subject: FARMACOLOGIA Year: 2022 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Opiate Alkaloids / Neoplasms Type of study: Diagnostic_studies / Guideline / Prognostic_studies Limits: Humans Language: En Journal: Pharm Stat Journal subject: FARMACOLOGIA Year: 2022 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom